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Cat. No.: HY-W700204

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N-(p-Aminophenethyl)spiperone

N-(p-Aminophenethyl) spiperone is a selective D₂-like dopamine receptor antagonist. N-(p-Aminophenethyl) spiperone binds to the ligand recognition sites of functional D₂ and D₃ dopamine receptors. N-(p-Aminophenethyl) spiperone serves as a research tool compound for labeling, localizing and identifying D₂ and D₃ dopamine receptors.

For research use only. We do not sell to patients.

CAS No.: 93801-18-4
Formula: C₃₁H₃₅FN₄O₂
Molecular Weight:514.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

N-(p-Aminophenethyl)spiperone Chemical Structure

CAS No.: 93801-18-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

All Dopamine Receptor Isoforms :

In Vitro

N-(p-aminophenethyl)spiperone can be radioiodinated to high specific activity and modified to a high-affinity photoaffinity probe, with iodination significantly enhancing its D₂-dopamine receptor binding affinity^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 93801-18-4
Molecular Weight 514.63
Formula C₃₁H₃₅FN₄O₂
SMILES

FC1=CC=C(C=C1)C(CCCN2CCC3(CC2)C(N(CN3C4=CC=CC=C4)CCC5=CC=C(C=C5)N)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Larson ER, et al. D3 and D2 dopamine receptors: visualization of cellular expression patterns in motor and limbic structures. Synapse. 1995;20(4):325-337. [Content Brief]

[2]. Amlaiky N, et al. Photoaffinity labeling of the D2-dopamine receptor using a novel high affinity radioiodinated probe. J Biol Chem. 1985;260(4):1983-1986. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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N-(p-Aminophenethyl)spiperone

All Dopamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

N-(p-Aminophenethyl)spiperone Related Classifications

HY-W700204 Related Classifications