943650-25-7
Chemical Structure
A-620223 succinate
Synonym(s): ABT-472
- CAS No.: 943650-25-7
- Formula:C20H28N4O5
- Molecular Weight:404.46
IUPAC Name: 2-(1-propylpiperidin-4-yl)-1H-benzo[d]imidazole-4-carboxamide succinate
InChIKey: GWFBXGWIRCSOAO-UHFFFAOYSA-N
SMILES: CCCN(CC1)CCC1C2=NC3=C(C(N)=O)C=CC=C3N2.O=C(O)CCC(O)=O
Biological Activity: A-620223 succinate (ABT-472) is an orally available poly(ADP-ribose) polymerase (PARP) inhibitor. A-620223 succinate (ABT-472) exhibits very good potency against the PARP-1 enzyme with a Ki value of 8 nM and an EC50 value of 3 nM in whole cell assay, making it useful in cancer research[1].
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A-620223 succinate | A-620223 succinate (ABT-472) is an orally available poly(ADP-ribose) polymerase (PARP) inhibitor. A-620223 succinate (ABT-472) exhibits very good potency against the PARP-1 enzyme with a Ki value of 8 nM and an EC50 value of 3 nM in whole cell assay, making it useful in cancer research. | |||||||||||||||||||||
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Keywords
