946414-98-8
946414-98-8
Chemical Structure
Eldelumab
Synonym(s): BMS-936557; MDX-1100
- CAS No.: 946414-98-8
- Formula:N/A
- Molecular Weight:(146.64 kDa)
IUPAC Name: tert-butyl (3-bromo-5-cyanophenyl)carbamate
SMILES: [Eldelumab]
Biological Activity: Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease[1][2].
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Eldelumab | 99.50% | Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease. | ||||||||||||||||||||
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References
- [1]. Gupta RK, et al. Drug repurposing for COVID-19 based on an integrative meta-analysis of SARS-CoV-2 induced gene signature in human airway epithelium. PLoS One. 2021 Sep 28;16(9):e0257784. [Content Brief]
- [2]. Asquith DL, et al. Targeting cell migration in rheumatoid arthritis. Curr Opin Rheumatol. 2015 Mar;27(2):204-11. [Content Brief]
Keywords
