2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. Eldelumab

Eldelumab  (Synonyms: BMS-936557; MDX-1100)

Cat. No.: HY-P99190 Purity: 95.00%
COA

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Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease.

For research use only. We do not sell to patients.

Eldelumab Chemical Structure

Eldelumab Chemical Structure

CAS No. : 946414-98-8

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1 mg USD 290 In-stock
5 mg USD 710 In-stock
10 mg USD 1100 In-stock
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Based on 1 publication(s) in Google Scholar

Eldelumab Related Antibodies

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Description

Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease[1][2].

IC50 & Target

CXCL10 (IP-10)[1][2].
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Eldelumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 95.00%

COA (291 KB)

Handling Instructions (2659 KB)
References
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Eldelumab Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eldelumab946414-98-8BMS-936557 MDX-1100BMS936557BMS 936557MDX1100MDX 1100MDX-1100CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsIgG1calcium fluxauto-inflammatory diseasesautoimmune diseasesrheumatoid arthritisulcerative colitiscrohn's diseaseInhibitorinhibitorinhibit

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