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Eldelumab

(Synonyms: BMS-936557; MDX-1100)
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Eldelumab (BMS-936557; MDX-1100) is a fully human IgG1 monoclonal antibody targeting IP-10 (CXCL10). Eldelumab binds and neutralizes IP-10, blocking TNF-α induction, disruption of endothelial junctional complexes, integrin activation, and activated T cell migration. Eldelumab selectively reduces TNF-α release in infected endothelial cells and restores Claudin5, Occludin, ZO-1, and VE-Cadherin expression. Eldelumab can be used for research on hand, foot, and mouth disease (HFMD) and ulcerative colitis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit : 99.50%
  • CAS. Nr.: 946414-98-8
  • Molecular Weight:146.64 kDa
  • Speicherung:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Eldelumab
  • Experimental Validation Results for Eldelumab
  • Eldelumab Chemical Structure
    Eldelumab Chemical Structure
CAS. Nr.: 946414-98-8
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Eldelumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human IP-10/CXCL10 Protein can bind Eldelumab. The EC50 for this effect is 1.68 ng/mL.

  • Eldelumab Chemical Structure
    1/16
  • Eldelumab
  • Immobilized Human IP-10/CXCL10 Protein can bind Eldelumab. The EC50 for this effect is 1.68 ng/mL.