955881-01-3
Chemical Structure
PF-04279405
- CAS No.: 955881-01-3
- Formula:C25H25FN4O4
- Molecular Weight:464.49
IUPAC Name: 4-(4-(azetidine-1-carbonyl)-3-fluorophenoxy)-2,2-dimethyl-N-(1-methyl-1H-pyrazol-3-yl)-2,3-dihydrobenzofuran-6-carboxamide
InChIKey: MDMLUBFZTGYEGP-UHFFFAOYSA-N
SMILES: O=C(C1=CC(OC2=CC=C(C(N3CCC3)=O)C(F)=C2)=C4CC(C)(C)OC4=C1)NC5=NN(C)C=C5
Biological Activity: PF-04279405 is a potent and full-acting glucokinase (GK) agonist (EC50=23 nM). Glucokinase (GK) is an enzyme responsible for the conversion of glucose to glucose-6-phosphate and plays a key role in maintaining blood glucose homeostasis. PF-04279405 can be used in the research of type 2 diabetes[1].
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PF-04279405 | PF-04279405 is a potent and full-acting glucokinase (GK) agonist (EC50=23 nM). Glucokinase (GK) is an enzyme responsible for the conversion of glucose to glucose-6-phosphate and plays a key role in maintaining blood glucose homeostasis. PF-04279405 can be used in the research of type 2 diabetes. | |||||||||||||||||||||
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Keywords
