CA/HDAC-IN-1
CA/HDAC-IN-1 (Compound 11) is a CA and HDAC inhibitor with Ki values of 7.4 nM, 31.0 nM, and 7.3 nM for hCA II, hCA IX, and hCA XII, respectively, and IC50 values of 0.21 μM and 3.60 μM for HDAC3 and HDAC8, respectively. CA/HDAC-IN-1 has anti-cancer activity against colon cancer, breast cancer, and melanoma.
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- Formel: C21H21N5O4S
- Molecular Weight:439.49
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
|
hCA II 7.4 nM (Ki) |
hCA XII 7.3 nM (Ki) |
HDAC3 0.21 μM (IC50) |
HDAC8 3.60 μM (IC50) |
hCA IX 31.0 nM (Ki) |
Chemical Information
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Molecular Weight 439.49
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Formel C21H21N5O4S
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SMILES
O=C(NC1=CC=CC=C1N)C2=CC=C(CNC(NC3=CC=C(S(=O)(N)=O)C=C3)=O)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CA/HDAC-IN-1 Related Classifications
HY-179271 Related Classifications
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