DB12055
DB12055 (MK-0767 analog) is a covalent SARS-CoV-2 3CL protease inhibitor. DB12055 has the potential for the study of dyslipidemia and diabetes mellitus.
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- CAS. Nr.: 934017-32-0
- Formel: C20H17F3N2O5
- Molecular Weight:422.35
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 934017-32-0
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Molecular Weight 422.35
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Formel C20H17F3N2O5
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SMILES
O=C(NCC1=CC=C(C(F)(F)F)C=C1)C2=CC(CC(OC(N3)=O)C3=O)=CC=C2OC
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Synonyms
MK-0767 analog
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Ronda K Rippley, et al. Human pharmacokinetics and interconversion of enantiomers of MK-0767, a dual PPARalpha/gamma agonist. J Clin Pharmacol. 2007 Mar;47(3):323-33. [Content Brief]
[2]. Ying Wang, et al. Multidimensional virtual screening approaches combined with drug repurposing to identify potential covalent inhibitors of SARS-CoV-2 3CL protease. J Biomol Struct Dyn. 2023;41(24):15262-15285. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)