Garbanzol
Based on 1 Customer Validation
Garbanzol is an orally active natural flavonoid compound. Garbanzol is one of the key intermediates in the flavonoid biosynthetic pathway. Garbanzol exhibits anti-mutagenic activity.
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- Reinheit: 98.0%
- CAS. Nr.: 1226-22-8
- Formel: C15H12O5
- Molecular Weight:272.25
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>100 μM
Compound: 8
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Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
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[PMID: 18440233] |
| B16-BL6 | IC50 |
>100 μM
Compound: 8
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Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
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[PMID: 18440233] |
| HeLa | IC50 |
>100 μM
Compound: 8
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Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
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[PMID: 18440233] |
| HT-1080 | IC50 |
>100 μM
Compound: 8
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Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
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[PMID: 18440233] |
| Lewis lung carcinoma cell line | IC50 |
>100 μM
Compound: 8
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Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
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[PMID: 18440233] |
In Vitro
Garbanzol (0.125-0.250 mg/plate; 48 h) exhibits no antimutagenic activity against aflatoxin B1-induced mutagenicity in Salmonella typhimurium TA100, but shows significant antimutagenic activity against MNNG-induced mutagenicity at 0.125 mg/plate and weak activity at 0.250 mg/plate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Parmacokinetics
| Species | Dose | Route | Cmax | AUC | Tmax | T1/2 | MRT0-t |
|---|---|---|---|---|---|---|---|
| Rat[2] | 1.154 mg/kg | p.o. | 0.24 | 0.41 | 0.60 h | 5.44 h | 2.52 h |
Chemical Information
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CAS. Nr. 1226-22-8
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Appearance Solid
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Molecular Weight 272.25
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Formel C15H12O5
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Color White to off-white
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SMILES
O[C@@H]1[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=CC=C3C1=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reinheit & Dokumentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Park KY, et al. Antimutagenic activity of flavonoids from the heartwood of Rhus verniciflua. J Ethnopharmacol. 2004;90(1):73-79. [Content Brief]
[2]. Jin MJ, et al. Pharmacokinetic Profile of Eight Phenolic Compounds and Their Conjugated Metabolites after Oral Administration of Rhus verniciflua Extracts in Rats. J Agric Food Chem. 2015;63(22):5410-5416. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Garbanzol Related Classifications
HY-N3926 Related Classifications
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