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Art. -Nr.: HY-N0859A

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Schisanhenol B

Schisanhenol B is one of the active ingredients of schisandra chinensis. Schisanhenol B is a tyrosinase inhibitor. Schisanhenol B has good binding activity with PIK3CG and can be used in the study of heart failure.

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CAS. Nr.: 102681-52-7
Formel: C₂₂H₂₆O₆
Molecular Weight:386.44

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Schisanhenol B Chemical Structure

CAS. Nr.: 102681-52-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle PI3K Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human A549 cells after 3 days by MTT assay Cytotoxicity against human A549 cells after 3 days by MTT assay	[PMID: 23738539]
HCT-116	IC₅₀	55.38 μM Compound: GM	Antiproliferative activity against human HCT-116 cells incubated for 24 hrs by alamar blue assay Antiproliferative activity against human HCT-116 cells incubated for 24 hrs by alamar blue assay	[PMID: 34038111]
HeLa	IC₅₀	17.15 μM Compound: GM	Antiproliferative activity against human HeLa cells assessed as increase in miR-21 biogenesis level measured after 24 hrs by luciferase assay Antiproliferative activity against human HeLa cells assessed as increase in miR-21 biogenesis level measured after 24 hrs by luciferase assay	[PMID: 34038111]
HeLa	IC₅₀	32.83 μM Compound: GM	Antiproliferative activity against human HeLa cells incubated for 24 hrs by alamar blue assay Antiproliferative activity against human HeLa cells incubated for 24 hrs by alamar blue assay	[PMID: 34038111]
HepG2	IC₅₀	27.26 μM Compound: GM	Antiproliferative activity against human HepG2 cells incubated for 24 hrs by alamar blue assay Antiproliferative activity against human HepG2 cells incubated for 24 hrs by alamar blue assay	[PMID: 34038111]
Huh-7	IC₅₀	32.23 μM Compound: GM	Antiproliferative activity against human Huh-7 cells incubated for 24 hrs by alamar blue assay Antiproliferative activity against human Huh-7 cells incubated for 24 hrs by alamar blue assay	[PMID: 34038111]
MCF7	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human MCF7 cells after 3 days by MTT assay Cytotoxicity against human MCF7 cells after 3 days by MTT assay	[PMID: 23738539]
MDA-MB-231	IC₅₀	56.61 μM Compound: GM	Antiproliferative activity against human MDA-MB-231 cells incubated for 24 hrs by alamar blue assay Antiproliferative activity against human MDA-MB-231 cells incubated for 24 hrs by alamar blue assay	[PMID: 34038111]
MHCC97	IC₅₀	24.75 μM Compound: GM	Antiproliferative activity against human MHCC97 cells incubated for 24 hrs by alamar blue assay Antiproliferative activity against human MHCC97 cells incubated for 24 hrs by alamar blue assay	[PMID: 34038111]
NB-4	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human NB4 cells after 3 days by MTT assay Cytotoxicity against human NB4 cells after 3 days by MTT assay	[PMID: 23738539]
PC-3	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human PC3 cells after 3 days by MTT assay Cytotoxicity against human PC3 cells after 3 days by MTT assay	[PMID: 23738539]
SH-SY5Y	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human SH-SY5Y cells after 3 days by MTT assay Cytotoxicity against human SH-SY5Y cells after 3 days by MTT assay	[PMID: 23738539]
SK-HEP1	IC₅₀	20.56 μM Compound: GM	Antiproliferative activity against human SK-HEP1 cells incubated for 24 hrs by alamar blue assay Antiproliferative activity against human SK-HEP1 cells incubated for 24 hrs by alamar blue assay	[PMID: 34038111]

Chemical Information

CAS. Nr. 102681-52-7
Molecular Weight 386.44
Formel C₂₂H₂₆O₆
SMILES

OC1=C(C(OC)=CC2=C1C3=C(C4=C(C=C3C[C@@H]([C@@H](C2)C)C)OCO4)OC)OC
Structure Classification
- Phenylpropanoids
- Lignans
- Phenols
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wen S, et al. Investigating the Mechanism of Action of Schisandra chinensis Combined with Coenzyme Q10 in the Treatment of Heart Failure Based on PI3K-AKT Pathway. Drug Des Devel Ther. 2023 Mar 27;17:939-957. [Content Brief]

[2]. Sobstyl E, et al. Chromatographic and Biological Screening of Chosen Species of Schisandraceae Family: Schisandra chinensis, S. rubriflora, S. sphenanthera, S. henryi and Kadsura japonica. Chem Biodivers. 2023 Oct;20(10):e202300741. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
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Chemical Information
Reinheit & Dokumentation
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Schisanhenol B

Alle PI3K Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Schisanhenol B Related Classifications

HY-N0859A Related Classifications