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Cat. No.: HY-149529

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HDAC8-IN-5

HDAC8-IN-5 (Compound 6a) is a HDAC8 inhibitor (IC₅₀: 28 nM). HDAC8-IN-5 can be used for cancer research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₁₂H₁₁N₃O₅
Masse moléculaire:277.23

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

HDAC8-IN-5 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

HDAC8-IN-5 (Compound 6a) is a HDAC8 inhibitor (IC₅₀: 28 nM). HDAC8-IN-5 can be used for cancer research^[1].

Voir tous les produits spécifiques à Isoform HDAC :

Chemical Information

Masse moléculaire 277.23
Formule C₁₂H₁₁N₃O₅
SMILES

O=C(NN(C(C1=C2C=CC=C1)=O)C2=O)C([H])NC(CO)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Guzmán Ramírez JE, et al. Synthesis of N-aminophalimides derived from α-amino acids: Theoretical study to find them as HDAC8 inhibitors by docking simulations and in vitro assays. Chem Biol Drug Des. 2023 Aug 28. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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HDAC8-IN-5

Voir tous les produits spécifiques à Isoform HDAC

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

HDAC8-IN-5 Related Classifications

HY-149529 Related Classifications