Tau-aggregation-IN-4
Tau-aggregation-IN-4 is a Tau-aggregation inhibitor (EC50 = 2.99 μM). Tau-aggregation-IN-4 can be used for the study of neurodegenerative disorders such as Alzheimer’s and Pick’s diseases.
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- Formel: C23H21N5O2
- Molecular Weight:399.45
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Tau-aggregation-IN-4 (Compound 1a) (10-30 μM, 24 h) scavenges tau aggregates at both 10 μM and 30 μM concentrations (EC50 = 2.99 μM) in SH-SY5Y cells, with an average maximum clearance of 62%, and is non-cytotoxic[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 399.45
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Formel C23H21N5O2
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SMILES
O=C(C1=CNC2=C1C=CC(NC(CCC3(CCC#C)N=N3)=O)=C2)NC4=CC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)