Deoxyfuconojirimycin hydrochloride
Based on 1 Customer Validation
Deoxyfuconojirimycin hydrochloride is a highly specific α-L-fucosidase inhibitor, with a Ki value of 10 nM against human liver lysosomal α-L-fucosidase and a Ki value of 140 nM against Charonia lampas α-L-fucosidase. Deoxyfuconojirimycin hydrochloride completely inhibits the activity of all soluble α-L-fucosidases in human liver, including multiple post-translationally generated enzyme forms. Deoxyfuconojirimycin hydrochloride exhibits no anti-human immunodeficiency virus activity.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 210174-73-5
- Formula: C6H14ClNO3
- Molecular Weight:183.63
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Deoxyfuconojirimycin hydrochloride exerts pH-dependent inhibitory effects, and its protonated form can form ion pairs with the carboxyl groups at the enzyme active site[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 210174-73-5
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Appearance Solid
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Molecular Weight 183.63
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Formula C6H14ClNO3
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Color Light brown to brown
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SMILES
O[C@@H]1[C@H](C)NC[C@@H](O)[C@@H]1O.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
H2O : ≥ 100 mg/mL (544.57 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.4457 mL | 27.2287 mL | 54.4573 mL | 136.1433 mL |
| 5 mM | 1.0891 mL | 5.4457 mL | 10.8915 mL | 27.2287 mL | |
| 10 mM | 0.5446 mL | 2.7229 mL | 5.4457 mL | 13.6143 mL | |
| 15 mM | 0.3630 mL | 1.8152 mL | 3.6305 mL | 9.0762 mL | |
| 20 mM | 0.2723 mL | 1.3614 mL | 2.7229 mL | 6.8072 mL | |
| 25 mM | 0.2178 mL | 1.0891 mL | 2.1783 mL | 5.4457 mL | |
| 30 mM | 0.1815 mL | 0.9076 mL | 1.8152 mL | 4.5381 mL | |
| 40 mM | 0.1361 mL | 0.6807 mL | 1.3614 mL | 3.4036 mL | |
| 50 mM | 0.1089 mL | 0.5446 mL | 1.0891 mL | 2.7229 mL | |
| 60 mM | 0.0908 mL | 0.4538 mL | 0.9076 mL | 2.2691 mL | |
| 80 mM | 0.0681 mL | 0.3404 mL | 0.6807 mL | 1.7018 mL | |
| 100 mM | 0.0545 mL | 0.2723 mL | 0.5446 mL | 1.3614 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Deoxyfuconojirimycin hydrochloride Related Classifications
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