ATP5PF - Atp5pf ATP synthase peripheral stalk subunit F6 Gene

Also Known as Atp5j

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 94271

Summary

Contributes to ATP hydrolysis activity. Involved in several processes, including negative regulation of icosanoid secretion; positive regulation of heart rate; and response to muscle activity. Located in cell surface; extracellular space; and mitochondrion. Part of mitochondrial proton-transporting ATP Synthase complex, coupling factor F(o). Used to study pulmonary hypertension. Biomarker of pulmonary hypertension. Orthologous to human ATP5PF (ATP Synthase peripheral stalk subunit F6). [provided by Alliance of Genome Resources, Apr 2022]

ATP5PF Products (1)

mRNA Protein Name
NM_053602.2 NP_446054.1 ATP synthase-coupling factor 6, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
contributes to ATP hydrolysis activity IDA
IDA: Inferred from direct assay
1829963 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
1429613 RGD
Biological Process GO Annotation Evidence Referencias Source
involved in negative regulation of arachidonate secretion IDA
IDA: Inferred from direct assay
9822642 RGD
involved in negative regulation of prostaglandin secretion IDA
IDA: Inferred from direct assay
11581303 RGD
involved in negative regulation of prostaglandin secretion IMP
IMP: Inferred from mutant phenotype
19474762 RGD
involved in positive regulation of blood pressure IDA
IDA: Inferred from direct assay
11581303 RGD
involved in positive regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
11581303 RGD
involved in positive regulation of heart rate IDA
IDA: Inferred from direct assay
12686462 RGD
involved in response to muscle activity IEP
IEP: Inferred from expression pattern
24719897 RGD
Cellular Component GO Annotation Evidence Referencias Source
located in cell surface IDA
IDA: Inferred from direct assay
11581303 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
27916219 RGD
part of proton-transporting ATP synthase complex IDA
IDA: Inferred from direct assay
17575325 RGD
part of proton-transporting ATP synthase complex, coupling factor F(o) IDA
IDA: Inferred from direct assay
10887193 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP synthase-coupling factor 6, mitochondrial

  • ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6

  • ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6

  • ATPase subunit F6

  • coupling factor 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS01212 ATP5PF Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ATP5PF NCBI NCBI:522