LY 255262
LY 255262 is an antibacterial agent. LY 255262 exhibits potent inhibitory effects against a variety of Gram-positive and Gram-negative bacteria in vitro. LY 255262 has MIC values of 64, 0.25, 0.5, 0.25, 0.25, 1, and 1 μg/mL for Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenza, Escherichia coli, Klebsiella, Enterobacter aerogenes, and Serratia, respectively. LY 255262 has a relatively weak inhibitory effect on Pseudomonas (MIC >128 μg/mL). LY 255262 can be used in antibacterial research.
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- No. CAS: 122620-16-0
- Fòrmula: C14H13N7O5S
- Peso molecular:391.36
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | CC50 |
60 μM
Compound: 31
|
Concentration required to reduce MRC-5 cell growth by 50%
Concentration required to reduce MRC-5 cell growth by 50%
|
[PMID: 10966740] |
| MRC5 | IC50 |
36 μM
Compound: 31
|
Concentration required to reduce viral plaque formation by Human Cytomegalovirus (HCMV) (strain AD-169) in MRC-5 cells
Concentration required to reduce viral plaque formation by Human Cytomegalovirus (HCMV) (strain AD-169) in MRC-5 cells
|
[PMID: 10966740] |
Chemical Information
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No. CAS 122620-16-0
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Peso molecular 391.36
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Fòrmula C14H13N7O5S
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SMILES
O=C(C1=C(C#N)CN(C[C@@H]2NC(/C(C3=CSC(N)=N3)=N\OC)=O)N1C2=O)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)