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Referencia número: HY-161751

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MJ34

MJ34 is a potent inhibitor of GSK-3β and GSK-3α, with the IC₅₀s of 15.4 nM and 31.5 nM, respectively. MJ34 plays an important role in cancer research

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No. CAS: 2099015-13-9
Fòrmula: C₁₉H₁₇N₅
Peso molecular:315.37

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

MJ34 Chemical Structure

No. CAS: 2099015-13-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
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Actividad biológica

Descripciòn

MJ34 is a potent inhibitor of GSK-3β and GSK-3α, with the IC₅₀s of 15.4 nM and 31.5 nM, respectively. MJ34 plays an important role in cancer research^[1]

IC₅₀ & Target

GSK-3β

15.4 nM (IC₅₀)

GSK-3α

31.5 nM (IC₅₀)

Ver todos los productos específicos de isoformas GSK-3 :

Chemical Information

No. CAS 2099015-13-9
Peso molecular 315.37
Fòrmula C₁₉H₁₇N₅
SMILES

NC1=NC=CC(C2=CNC3=NC=C(C=C32)C4=C(CC)C=CC=C4)=N1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Mir Owais Ayaz, et al. Identification of a novel GSK3β inhibitor involved in abrogating KRas dependent pancreatic tumors in Wnt/beta-catenin and NF-kB dependent manner. Life Sci. 2024 Aug 15:351:122840. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=

Concentration Concentration

×

Volume Volume

×

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

×

Volume _(start) Volume _(start)

=

Concentration _(final) Concentration _(final)

×

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias