GDP-Fucose-Tz
GDP-Fucose-Tz (GDP-Fucose-Am-Tz) is a non-natural GDP-fucose analog bearing a Tetrazine group. As a precursor, GDP-Fucose-Tz enables the synthesis of GDP-fucose-ssDNA probes via inverse electron demand Diels-Alder reaction. GDP-Fucose-Tz participates in chemoenzymatic reactions to prepare GDP-fucose-Herceptin derivatives through conjugation with TCO-Herceptin.
For research use only. We do not sell to patients.
- CAS No.: 2762518-76-1
- Formula: C36H52N10O21P2
- Molecular Weight:1022.80
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
GDP-Fucose-Tz reacts with TCO-ssDNA at a molar ratio of 1:1 to yield the final product GDP-fucose-ssDNA[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2762518-76-1
-
Molecular Weight 1022.80
-
Formula C36H52N10O21P2
-
SMILES
O=C1NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](COP(OP(O[C@H]4O[C@@H](CNC(CCOCCOCCOCCOCCOC5=CC=C(C6=NN=C(C)N=N6)C=C5)=O)[C@@H](O)[C@@H](O)[C@@H]4O)(O)=O)(O)=O)[C@@H](O)[C@H]3O
-
Synonyms
GDP-Fucose-Am-Tz
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yu W, et al. Chemoenzymatic Measurement of LacNAc in Single-Cell Multiomics Reveals It as a Cell-Surface Indicator of Glycolytic Activity of CD8+ T Cells. J Am Chem Soc. 2023;145(23):12701-12716. [Content Brief]
[2]. Ding H, et al. Thermoelectric Nanofluidics Probing Thermal Heterogeneity inside Single Cells. J Am Chem Soc. 2023;145(41):22433-22441. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GDP-Fucose-Tz Related Classifications
HY-160258 Related Classifications
Powered by Bioz