DDR1 - discoidin domain receptor tyrosine kinase 1 Gene
Species: Macaca fascicularis
Gene Type: protein coding
Gene ID: 102123648
About DDR1
Primary_assembly 4: 139,693,271-139,709,275 reverse strand.Macaca_fascicularis_6.0:CM021942.1
This gene has 5 transcripts (splice variants), 196 orthologues and 55 paralogues.
DDR1 Products (13)
| mRNA | Protein | Name |
|---|---|---|
| XM_005553607.3 | XP_005553664.1 | epithelial discoidin domain-containing receptor 1 isoform X3 |
| XM_045390062.1 | XP_045245997.1 | epithelial discoidin domain-containing receptor 1 isoform X3 |
| XM_015449649.2 | XP_015305135.1 | epithelial discoidin domain-containing receptor 1 isoform X1 |
| XM_015449658.2 | XP_015305144.1 | epithelial discoidin domain-containing receptor 1 isoform X4 |
| XM_045390060.1 | XP_045245995.1 | epithelial discoidin domain-containing receptor 1 isoform X3 |
| XM_045390059.1 | XP_045245994.1 | epithelial discoidin domain-containing receptor 1 isoform X3 |
| XM_015449656.2 | XP_015305142.1 | epithelial discoidin domain-containing receptor 1 isoform X3 |
| XM_045390064.1 | XP_045245999.1 | epithelial discoidin domain-containing receptor 1 isoform X6 |
| XM_005553608.3 | XP_005553665.1 | epithelial discoidin domain-containing receptor 1 isoform X3 |
| XM_045390057.1 | XP_045245992.1 | epithelial discoidin domain-containing receptor 1 isoform X2 |
| XM_045390063.1 | XP_045245998.1 | epithelial discoidin domain-containing receptor 1 isoform X5 |
| XM_045390058.1 | XP_045245993.1 | epithelial discoidin domain-containing receptor 1 isoform X3 |
| XM_045390061.1 | XP_045245996.1 | epithelial discoidin domain-containing receptor 1 isoform X3 |
DDR1 Protein Structure
FA58C
FA58C: cd00057 (85 - 209)
PTKc_DDR1
PTKc_DDR1: cd05096 (629 - 932)
- 0
- 200
- 400
- 600
- 800
- 939 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
epithelial discoidin domain-containing receptor 1 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-16961 | Sitravatinib | Inhibitor | 99.57% | Phase 3 |
| HY-16961A | Sitravatinib malate | Inhibitor | / | Phase 3 |
| HY-157442 | GLPG3312 | Inhibitor | 98.63% | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(17)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-135401 | VU6015929 | Inhibitor | 99.50% | Unkown |
| HY-114173 | DDR1-IN-4 | Inhibitor | 98.19% | Unkown |
| HY-NP175 | Collagen (bovine skin) | Ligand | / | Unkown |
| HY-133670 | DDR1-IN-6 | Inhibitor | 98.02% | Unkown |
| HY-156552 | DDR1/2 inhibitor-2 | Inhibitor | 99.73% | Unkown |
| HY-13979A | DDR1-IN-1 dihydrochloride | Inhibitor | 98.92% | Unkown |
| HY-133669 | DDR1-IN-5 | Inhibitor | 99.65% | Unkown |
| HY-176184 | PROTAC DDR1 degrader-1 | Degrader | 98.69% | Unkown |
| HY-167208 | SR-302 | Inhibitor | 98.51% | Unkown |
| HY-183068 | AP4-43 | Inhibitor | / | Unkown |
| HY-176185 | DDR1 ligand 1 | / | Unkown | |
| HY-175281 | SJ11646 | Degrader | / | Unkown |
| HY-179535 | Axl-IN-21 | Inhibitor | / | Unkown |
| HY-173284 | DDR1-IN-11 | Inhibitor | / | Unkown |
| HY-181839 | DDR1/2 IN-4 | Inhibitor | / | Unkown |
| HY-122848 | DDR1/2 inhibitor-3 | Inhibitor | / | Unkown |
| HY-162102 | DDR1-IN-8 | Inhibitor | / | Unkown |
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