DDR1/2 inhibitor-3
DDR1/2 inhibitor-3 (5n) is a DDR1/2 inhibitor, with IC50 valuesof 9.4 and 20.4 nM, respectively. DDR1/2 inhibitor-3 can be used in anti-inflammatory research.
For research use only. We do not sell to patients.
- CAS No.: 2241813-33-0
- Formula: C31H31F3N6O
- Molecular Weight:560.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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DDR1 9.4 nM (IC50) |
DDR2 20.4 nM (IC50) |
Chemical Information
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CAS No. 2241813-33-0
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Molecular Weight 560.61
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Formula C31H31F3N6O
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SMILES
O=C(NC1=CC(C(F)(F)F)=CC(CN2CCN(C)CC2)=C1)C3=CC=C(C(C)C)C(C#CC4=CN=C5C=NC=CN54)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang Z, et al. Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2. J Med Chem. 2018 Sep 13;61(17):7977-7990. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)