DDR1-IN-8
DDR1-IN-8 (compound 7s) is a potent inhibitor of DDR1/2, with the IC50 values of 0.045 μM and 0.126 μM, respectively. DDR1-IN-8 has anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 3038810-92-0
- Formula: C23H24F3N5O2
- Molecular Weight:459.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
DDR1 |
DDR2 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
1.84 μM
Compound: 7s
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 38171149] |
| NCI-H1975 | IC50 |
1.87 μM
Compound: 7s
|
Antiproliferative activity against human NCI-H1975 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H1975 cells incubated for 72 hrs by MTT assay
|
[PMID: 38171149] |
Chemical Information
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CAS No. 3038810-92-0
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Molecular Weight 459.46
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Formula C23H24F3N5O2
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SMILES
O=C(NCC1=CN(CC(N2CCN(CC2)C)=O)C3=C1C=C(F)C=C3)NC4=CC=C(C=C4F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)