Adcy3 - adenylate cyclase 3 Gene

Also Known as AC3; ACIII; mKIAA0511

Species: Mus musculus

Gene Type: protein coding
Gene ID: 104111

Summary

Enables Adenylate Cyclase activity. Involved in several processes, including cAMP biosynthetic process; cellular response to forskolin; and olfactory learning. Acts upstream of or within sensory perception of smell. Located in ciliary membrane. Is integral component of membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human ADCY3 (Adenylate Cyclase 3). [provided by Alliance of Genome Resources, Apr 2022]

Adcy3 Products (3)

mRNA Protein Name
NM_001159536.1 NP_001153008.1 adenylate cyclase type 3 isoform 2
NM_001159537.1 NP_001153009.1 adenylate cyclase type 3 isoform 2
NM_138305.3 NP_612178.2 adenylate cyclase type 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables adenylate cyclase activity IMP
IMP: Inferred from mutant phenotype
11055432 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12122055 MGI
Biological Process GO Annotation Evidence References Source
involved in acrosome reaction IMP
IMP: Inferred from mutant phenotype
15705663 MGI
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
11055432 MGI
involved in cAMP biosynthetic process IMP
IMP: Inferred from mutant phenotype
11055432 MGI
involved in cellular response to forskolin IMP
IMP: Inferred from mutant phenotype
11055432 MGI
involved in flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
15705663 MGI
involved in olfactory learning IMP
IMP: Inferred from mutant phenotype
11055432 MGI
acts upstream of or within sensory perception of smell IDA
IDA: Inferred from direct assay
23077041 MGI
involved in sensory perception of smell IMP
IMP: Inferred from mutant phenotype
11055432 MGI
involved in single fertilization IMP
IMP: Inferred from mutant phenotype
15705663 MGI
Cellular Component GO Annotation Evidence References Source
located in ciliary membrane IDA
IDA: Inferred from direct assay
28053034 MGI
located in cilium IDA
IDA: Inferred from direct assay
11055432 MGI
located in membrane IDA
IDA: Inferred from direct assay
11055432 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenylate cyclase type 3

  • AC-III

  • ATP pyrophosphate-lyase 3

  • adenylate cyclase type III

  • adenylate cyclase, olfactive type

  • adenylyl cyclase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00329 ADCY3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00334 ADCY8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20851 Adcy3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27365 Adcy3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adcy3 NCBI NCBI:109