C1QTNF3 - C1q and TNF related 3 Gene

Homo sapiens

Also known as CORS; CORCS; CTRP3; CORS26; C1ATNF3; CORS-26

Gene ID: 114899 | Gene type: protein coding

About C1QTNF3

Cytogenetic location: 5p13.2 Genomic coordinates (GRCh38): 5:34,017,858-34,244,724 (from NCBI)

This gene has 6 transcripts (splice variants), 117 orthologues and 23 paralogues. Broad expression in esophagus (RPKM 12.4), urinary bladder (RPKM 10.0) and 21 other tissues.

Summary

Enables identical protein binding activity. Involved in several processes, including cellular triglyceride homeostasis; negative regulation of NIK/NF-kappaB signaling; and regulation of cytokine production. Acts upstream of or within negative regulation of gluconeogenesis. Located in extracellular exosome and membrane. [provided by Alliance of Genome Resources, Apr 2022]

C1QTNF3 Products(2)

mRNA	Protein	Name
NM_030945.4	NP_112207.1	complement C1q tumor necrosis factor-related protein 3 isoform a precursor
NM_181435.6	NP_852100.3	complement C1q tumor necrosis factor-related protein 3 isoform b precursor

C1QTNF3 Protein Structure

Collagen

C1q

0
100
200
246 a.a.

Protein Preferred Names

Protein Names

complement C1q tumor necrosis factor-related protein 3

C1q and tumor necrosis factor related protein 3

Recombinant C1QTNF3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71648	C1QTNF3/CTRP3 Protein, Human (His)	Q9BXJ4 (23Q-246K)	≥95%

Related Diseases

Diseases

Alias

Cataract 31, Multiple Types

Cataract, Posterior Polar, 3	Ctpp3
Cataract 31 Multiple Types	CTRCT31
Cpp3	Posterior Polar Cataract 3
Cataract, Type 31, Multiple Types

Chromosome 5p13 Duplication Syndrome

5p13 Microduplication Syndrome	Trisomy 5p13
Dup(5)(P13)

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01729	C1QTNF3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	C1QTNF3	MGD	MGI:1932136
Rattus norvegicus	C1QTNF3	RGD	RGD:1305010
Others	C1QTNF3	NCBI

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