Pacs1 - phosphofurin acidic cluster sorting protein 1 Gene

Also Known as Pacs-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171444

Summary

Predicted to enable transmembrane transporter binding activity. Involved in cellular protein localization and positive regulation of protein binding activity. Located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in Schuurs-Hoeijmakers Syndrome. Orthologous to human PACS1 (phosphofurin acidic cluster sorting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pacs1 Products (1)

mRNA Protein Name
NM_134406.1 NP_599233.1 phosphofurin acidic cluster sorting protein 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
9695949 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphofurin acidic cluster sorting protein 1

  • cytosolic sorting protein PACS-1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-13523 PAC-1 99.88% Phase 2
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99509 Zelminemab Inhibitor 98.79% Phase 2

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0221 PACAP (1-38), human, ovine, rat Inducer 99.99% Unkown
HY-P0176 PACAP (1-27), human, ovine, rat 99.30% Unkown
HY-P0221C PACAP (1-38) free acid 99.94% Unkown
HY-133529 PA-8 97.00% Unkown
HY-147557 PA-915 Antagonist 99.17% Unkown
HY-P0176A PACAP (1-27), human, ovine, rat TFA 99.81% Unkown
HY-129421 PA-9 99.73% Unkown
HY-159632 PAR4 antagonist 6 Antagonist 99.35% Unkown
HY-160694 cBu-Cit-GAL-02-221 Degrader / Unkown
HY-129937 (S)-GNE-987 Inhibitor / Unkown
HY-13523S PAC-1-d8 / Unkown
HY-P0221A PACAP (1-38), human, ovine, rat TFA Inducer / Unkown
HY-P3483 Maxadilan / Unkown
HY-RS09955 PACS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119158 VU0652925 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pacs1 NCBI NCBI:55690