DRG2 - developmentally regulated GTP binding protein 2 Gene

Homo sapiens

Gene ID: 1819 | Gene type: protein coding

About DRG2

Cytogenetic location: 17p11.2 Genomic coordinates (GRCh38): 17:18,087,948-18,107,969 (from NCBI)

This gene has 21 transcripts (splice variants), 215 orthologues and 4 paralogues. Ubiquitous expression in ovary (RPKM 11.9), prostate (RPKM 10.9) and 25 other tissues.

Summary

This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jan 2012]

DRG2 Products(2)

mRNA	Protein	Name
NM_001330144.2	NP_001317073.1	developmentally-regulated GTP-binding protein 2 isoform 2
NM_001388.5	NP_001379.1	developmentally-regulated GTP-binding protein 2 isoform 1

DRG2 Protein Structure

MMR_HSR1

TGS

0
100
200
300
364 a.a.

Protein Preferred Names

Protein Names

developmentally-regulated GTP-binding protein 2

TRAFAC GTPase DRG2

Related Diseases

Diseases

Alias

Smith-Magenis Syndrome

SMS	Chromosome 17p11.2 Deletion Syndrome
17p11.2 Microdeletion Syndrome	17p11.2 Monosomy
Chromosome 17p Deletion Syndrome	Del(17)
P11.2	17p- Syndrome
Deletion 17p Syndrome	Partial Monosomy 17p

Volkmann Contracture

Ischemic Contracture

Volkmann'S Ischemic Contracture

Radial Neuropathy

Potocki-Lupski Syndrome

PTLS	Chromosome 17p11.2 Duplication Syndrome
17p11.2 Microduplication Syndrome	Duplication 17p11.2 Syndrome
Trisomy 17p11.2	Potocki-Lupski Syndrome (Dup(17)(P11.2p11.2))
17p11.2 Duplication Syndrome	Dup(17)(P11.2p11.2)
Pls	Chromosome 17, Trisomy 17p11 2

Craniometaphyseal Dysplasia, Autosomal Dominant

Craniometaphyseal Dysplasia	CMDD
Cmdj	Cmd
Autosomal Dominant Craniometaphyseal Dysplasia	Craniometaphyseal Dysplasia, Jackson Type
Craniometaphyseal Dysplasia Jackson Type	Autosomal Recessive Craniometaphyseal Dysplasia
Cmdr	Dysplasia, Craniometaphyseal, Autosomal Dominant
Craniometaphyseal Dysplasia, Autosomal Recessive Type

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04010	DRG2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	DRG2	VGNC	VGNC:28209
Felis catus	DRG2	VGNC	VGNC:61631
Canis familiaris	DRG2	VGNC	VGNC:40098
Rattus norvegicus	DRG2	RGD	RGD:1562380
Mus musculus	DRG2	MGD	MGI:1342307
Macaca mulatta	DRG2	VGNC	VGNC:71993