RWDD1 - RWD domain containing 1 Gene

Also Known as CGI-24; PTD013

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51389

About RWDD1

This gene has 6 transcripts (splice variants) and 237 orthologues. Ubiquitous expression in fat (RPKM 22.0), adrenal (RPKM 19.3) and 25 other tissues.

Summary

Predicted to be involved in several processes, including cellular response to lipid; cytoplasmic translation; and positive regulation of Androgen Receptor activity. Predicted to be located in cytoplasm. Predicted to be part of polysome. [provided by Alliance of Genome Resources, Apr 2022]

RWDD1 Products (3)

mRNA Protein Name
NM_001007464.3 NP_001007465.1 RWD domain-containing protein 1 isoform b
NM_015952.4 NP_057036.2 RWD domain-containing protein 1 isoform a
NM_016104.4 NP_057188.2 RWD domain-containing protein 1 isoform b

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RWDD1 Protein Structure

RWD

RWD: RWD domain (4 - 111)

  • 0
  • 100
  • 200
  • 243 a.a.
Protein Preferred Names Protein Names

RWD domain-containing protein 1

  • DRG family-regulatory protein 2

RWDD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RWDD1 Q9H446 DRG1 Homo sapiens Q9Y295
Validated Y2H
25416956
Intra
RWDD1 Q9H446 DRG1 Homo sapiens Q9Y295
Validated Y2H
32296183
Intra
RWDD1 Q9H446 DRG2 Homo sapiens P55039
Y2H Array
25416956
Intra
RWDD1 Q9H446 DRG2 Homo sapiens P55039
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Potocki-Lupski Syndrome

  • PTLS

  • Chromosome 17p11.2 Duplication Syndrome

  • 17p11.2 Microduplication Syndrome

  • Duplication 17p11.2 Syndrome

  • Trisomy 17p11.2

  • Potocki-Lupski Syndrome (Dup(17)(P11.2p11.2))

  • 17p11.2 Duplication Syndrome

  • Dup(17)(P11.2p11.2)

  • Pls

  • Chromosome 17, Trisomy 17p11 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12356 RWDD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RWDD1 VGNC VGNC:45813
Rattus norvegicus RWDD1 RGD RGD:631337
Mus musculus RWDD1 MGD MGI:1913771
Felis catus RWDD1 VGNC VGNC:64827
Bos taurus RWDD1 VGNC VGNC:34225
Macaca mulatta RWDD1 VGNC VGNC:77070
Others RWDD1 NCBI