Tbxa2r - thromboxane A2 receptor Gene

Rattus norvegicus

Gene ID: 24816 | Gene type: protein coding

About Tbxa2r

Primary_assembly 7: 8,383,378-8,388,176 reverse strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 193 orthologues, 8 paralogues and is associated with 22 phenotypes. Biased expression in Thymus (RPKM 14.9), Lung (RPKM 32.5) and 7 other tissues.

Summary

Enables thromboxane receptor activity. Involved in several processes, including cellular response to lipopolysaccharide; positive regulation of vasoconstriction; and response to testosterone. Located in acrosomal vesicle and plasma membrane. Used to study adult respiratory distress syndrome; kidney failure; thrombocytopenia; and toxic shock syndrome. Human ortholog(s) of this gene implicated in aspirin-induced respiratory disease; asthma; and blood platelet disease. Orthologous to human TBXA2R (thromboxane A2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Tbxa2r Products(1)

mRNA	Protein	Name
NM_017054.2	NP_058750.2	thromboxane A2 receptor

Tbxa2r Protein Structure

7tm_GPCRs

0
100
200
300
341 a.a.

Protein Preferred Names

Protein Names

thromboxane A2 receptor

TXA2-R	TXR2
Thromboxane receptor	prostanoid TP receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS14283	TBXA2R Human Pre-designed siRNA Set A	/	Unkown
HY-RS14284	Tbxa2r Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS14285	Tbxa2r Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tbxa2r	NCBI	NCBI:6915

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