Syn1 - synapsin I Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24949

Summary

Enables calcium-dependent protein binding activity. Involved in neuron development and synapse organization. Located in several cellular components, including dendrite; presynaptic active zone; and synaptic vesicle. Is anchored component of synaptic vesicle membrane. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in X-linked epilepsy with variable learning disabilities and behavior disorders and non-syndromic X-linked intellectual disability 50. Orthologous to human SYN1 (synapsin I). [provided by Alliance of Genome Resources, Apr 2022]

Syn1 Products (2)

mRNA Protein Name
NM_001110782.2 NP_001104252.1 synapsin-1 isoform b
NM_019133.2 NP_062006.1 synapsin-1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium-dependent protein binding IPI
IPI: Inferred from physical interaction
10567243 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11867766 RGD
Biological Process GO Annotation Evidence References Source
involved in neuron development IEP
IEP: Inferred from expression pattern
27228907 RGD
involved in synapse organization IMP
IMP: Inferred from mutant phenotype
22045728 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
1419001 RGD
is active in extrinsic component of synaptic vesicle membrane EXP
EXP: Inferred from Experiment
23622064 RGD
is active in extrinsic component of synaptic vesicle membrane IDA
IDA: Inferred from direct assay
6404912 RGD
located in presynaptic active zone IDA
IDA: Inferred from direct assay
21119615 RGD
located in synapse IDA
IDA: Inferred from direct assay
24613359 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
11867766 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synapsin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16954 Sdc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14079 SYN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14317 TCL1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22337 Syn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28859 Syn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syn1 NCBI NCBI:6853