Atp1b1 - ATPase Na+/K+ transporting subunit beta 1 Gene

Also Known as ATPBS

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25650

Summary

Enables P-type sodium:potassium-exchanging transporter activity and protein heterodimerization activity. Involved in potassium ion transport; response to hypoxia; and sodium ion transport. Located in apical plasma membrane; basolateral plasma membrane; and caveola. Part of sodium:potassium-exchanging ATPase complex. Biomarker of sensorineural hearing loss. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human ATP1B1 (ATPase Na+/K+ transporting subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Atp1b1 Products (1)

mRNA Protein Name
NM_013113.2 NP_037245.2 sodium/potassium-transporting ATPase subunit beta-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables P-type sodium:potassium-exchanging transporter activity IDA
IDA: Inferred from direct assay
16624992 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14749213 RGD
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
28787093 RGD
Biological Process GO Annotation Evidence References Source
involved in metal ion transport IDA
IDA: Inferred from direct assay
15327400 RGD
involved in potassium ion transport IDA
IDA: Inferred from direct assay
16624992 RGD
involved in response to hypoxia IDA
IDA: Inferred from direct assay
12573531 RGD
involved in sodium ion transport IDA
IDA: Inferred from direct assay
16624992 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
14749213 RGD
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
15327400 RGD
located in caveola IDA
IDA: Inferred from direct assay
16624992 RGD
located in membrane IDA
IDA: Inferred from direct assay
28787093 RGD
part of sodium:potassium-exchanging ATPase complex IDA
IDA: Inferred from direct assay
16624992 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium/potassium-transporting ATPase subunit beta-1

  • ATPase, Na+/K+ transporting, beta 1 polypeptide

  • Na,K-ATPase beta 1 subunit

  • sodium/potassium-dependent ATPase subunit beta-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1565A Transdermal Peptide Disulfide TFA Inhibitor 99.95% Unkown
HY-P1565 Transdermal Peptide Disulfide Inhibitor 98.79% Unkown
HY-RS01186 ATP1B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21097 Atp1b1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27615 Atp1b1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp1b1 NCBI NCBI:481