Sap130 - Sin3A associated protein Gene

Also Known as 6720406D06; 2610304F09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 269003

Summary

Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nuclear speck. Predicted to be part of Sin3-type complex. Used to study congenital heart disease and hypoplastic left heart syndrome. Orthologous to human SAP130 (Sin3A associated protein 130). [provided by Alliance of Genome Resources, Apr 2022]

Sap130 Products (3)

mRNA Protein Name
NM_001357554.1 NP_001344483.1 histone deacetylase complex subunit SAP130 isoform 2
NM_001357555.1 NP_001344484.1 histone deacetylase complex subunit SAP130 isoform 3
NM_172965.3 NP_766553.1 histone deacetylase complex subunit SAP130 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18776906 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone deacetylase complex subunit SAP130

  • 130 kDa Sin3-associated polypeptide

  • Sin3A associated protein, 130kDa

  • sin3-associated polypeptide p130

Recombinant Sap130 Proteins

Cat. No. Product Name Accession Purity
HY-P71592 Sap130 Protein, Mouse (His) Q8BIH0-1 (P845-V1057) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12437 SAP130 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12762 SF3B3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18715 Sap130 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20489 Sf3b3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25202 Sap130 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sap130 NCBI NCBI:79595