CXCL8 - C-X-C motif chemokine ligand 8 Gene

Bos taurus

Also known as IL8; IL-8

Gene ID: 280828 | Gene type: protein coding

About CXCL8

Primary_assembly 6: 88,810,418-88,814,572 forward strand.ARS-UCD1.2:CM008173.2

This gene has 1 transcript (splice variant), 178 orthologues and 10 paralogues.

mRNA	Protein	Name
NM_173925.2	NP_776350.1	interleukin-8 precursor

Chemokine_CXC

Protein Preferred Names

Protein Names

interleukin-8

C-X-C motif chemokine 8	chemokine (C-X-C motif) ligand 8
neutrophil activating peptide 1

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-19768	Danirixin	Antagonist	98.19%	Phase 2

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P990598	Adakitug	Inhibitor	≥99.0%	Phase 2
HY-P990313	ABX-IL8		98.70%	Phase 2

Pre-clinical Phase

Bioactive Molecules (13)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12927	SX-517	Antagonist	99.90%	Unkown
HY-P10300	CXCL8 (54-72)		99.90%	Unkown
HY-136239	Beclomethasone 17-propionate	Agonist	99.52%	Unkown
HY-120595	JNJ-49095397	Inhibitor	99.55%	Unkown
HY-163475	CXCL-CXCR1/2-IN-1	Inhibitor	99.64%	Unkown
HY-P10552	pCXCL8-1aa	Inhibitor	98.13%	Unkown
HY-RS03395	CXCL8 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-106463	Hexaprofen		/	Unkown
HY-119234	CX4338		/	Unkown
HY-144780	CXCR2 antagonist 4	Antagonist	/	Unkown
HY-175813	NPSR1 antagonist-1		/	Unkown
HY-P5923	E70K		/	Unkown
HY-174729	Human CXCL8 mRNA		/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990392	Anti-CXCL8/IL-8 Antibody		99.51%	Unkown

Species	Symbol	Source	ID
Homo sapiens	CXCL8	NCBI	NCBI:3576
Canis familiaris	CXCL8	NCBI	NCBI:403850
Macaca fascicularis	CXCL8	NCBI	NCBI:102127272
Susscrofa domestica	CXCL8	NCBI
Macaca mulatta	CXCL8	NCBI	NCBI:613028

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