1. GPCR/G Protein
    Immunology/Inflammation
  2. CXCR
  3. CXCR2 antagonist 4

CXCR2 antagonist 4 

Cat. No.: HY-144780
Handling Instructions

CXCR2 antagonist 4 (compound 7) is a potent CXCR2 antagonist with an IC50 value of 0.13 μM. CXCR2 antagonist 4 can inhibit CXCL8-induced cytosolic calcium increase (IC50 = 27 μM). CXCR2 antagonist 4 can be used for researching anticancer.

For research use only. We do not sell to patients.

CXCR2 antagonist 4 Chemical Structure

CXCR2 antagonist 4 Chemical Structure

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Description

CXCR2 antagonist 4 (compound 7) is a potent CXCR2 antagonist with an IC50 value of 0.13 μM. CXCR2 antagonist 4 can inhibit CXCL8-induced cytosolic calcium increase (IC50 = 27 μM). CXCR2 antagonist 4 can be used for researching anticancer[1].

IC50 & Target[1]

CXCR2

0.13 μM (IC50)

Molecular Weight

368.42

Formula

C15H14F2N4OS2

SMILES

OC[[email protected]@H](C)NC1=C2SC=NC2=NC(SCC3=CC=CC(F)=C3F)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
CXCR2 antagonist 4
Cat. No.:
HY-144780
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