Mki67 - marker of proliferation Ki-67 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291234

Summary

Predicted to enable protein C-terminus binding activity. Involved in several processes, including DNA metabolic process; animal organ regeneration; and cellular response to heat. Located in nucleus. Used to study high grade glioma; leiomyoma; and prostate carcinoma. Biomarker of colon cancer; kidney disease; mucositis; type 2 diabetes mellitus; and urinary bladder Cancer. Human ortholog(s) of this gene implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic Cancer. Orthologous to human MKI67 (marker of proliferation Ki-67). [provided by Alliance of Genome Resources, Apr 2022]

Mki67 Products (1)

mRNA Protein Name
NM_001271366.1 NP_001258295.1 proliferation marker protein Ki-67

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in DNA metabolic process IEP
IEP: Inferred from expression pattern
9303485 RGD
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
9303485 RGD
involved in cellular response to heat IEP
IEP: Inferred from expression pattern
9631633 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
16987298 RGD
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12368262 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proliferation marker protein Ki-67

  • antigen KI-67

  • antigen identified by monoclonal antibody Ki-67

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175266 MI1013 99.10% Unkown
HY-RS08470 MKI67 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21649 Mki67 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28167 Mki67 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mki67 NCBI NCBI:4288