2. Gene
  3. Pou5f1 - POU class 5 homeobox 1 Gene

Pou5f1 - POU class 5 homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 294562 | Gene type: protein coding

About Pou5f1

Primary_assembly 20: 3,223,129-3,227,891 reverse strand.mRatBN7.2:CM026993.1

This gene has 1 transcript (splice variant), 331 orthologues, 16 paralogues and is associated with 12 phenotypes. Biased expression in Liver (RPKM 6.5), Thymus (RPKM 3.2) and 8 other tissues.

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; protein domain specific binding activity; and sequence-specific DNA binding activity. Involved in regulation of transcription, DNA-templated and response to cytokine. Located in nucleus. Human ortholog(s) of this gene implicated in embryonal carcinoma and seminoma. Orthologous to several human genes including POU5F1 (POU class 5 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Pou5f1 Products(1)

mRNA Protein Name
NM_001009178.2 NP_001009178.1 POU domain, class 5, transcription factor 1

Pou5f1 Protein Structure

POU

POU: smart00352 (130 - 204)

Homeobox

Homeobox: pfam00046 (225 - 278)

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  • 352 a.a.
Protein Preferred Names Protein Names

POU domain, class 5, transcription factor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10907 POU5F1 Human Pre-designed siRNA Set A / Unkown
HY-RS10908 Pou5f1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS10909 Pou5f1 Rat Pre-designed siRNA Set A / Unkown
HY-RS10910 POU5F1B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou5f1 NCBI NCBI:5460