Frzb - frizzled-related protein Gene

Predicted to enable Wnt-protein binding activity. Predicted to be involved in several processes, including Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; and negative regulation of cell growth. Predicted to act upstream of or within several processes, including animal organ development; negative regulation of cell differentiation; and positive regulation of fat cell differentiation. Predicted to be active in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human FRZB (Frizzled related protein). [provided by Alliance of Genome Resources, Apr 2022]