Siglec1 - sialic acid binding Ig like lectin 1 Gene

Predicted to enable virion binding activity. Predicted to be involved in clathrin-dependent endocytosis of virus by host cell and negative regulation of phagocytosis. Predicted to act upstream of or within positive regulation of T cell apoptotic process and positive regulation of extrinsic apoptotic signaling pathway. Predicted to be located in endocytic vesicle. Predicted to be active in early endosome; late endosome; and plasma membrane. Orthologous to human SIGLEC1 (sialic acid binding Ig like lectin 1). [provided by Alliance of Genome Resources, Apr 2022]