Pip5k1c - phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 314641

Summary

Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity and talin binding activity. Predicted to be involved in regulation of postsynaptic neurotransmitter receptor internalization and regulation of synaptic vesicle endocytosis. Predicted to act upstream of or within axonogenesis; phosphatidylinositol biosynthetic process; and platelet aggregation. Is active in presynaptic endocytic zone membrane. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma). [provided by Alliance of Genome Resources, Apr 2022]

Pip5k1c Products (2)

mRNA Protein Name
NM_001009967.2 NP_001009967.2 phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform c
NM_001033970.1 NP_001029142.1 phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform b

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in presynaptic endocytic zone membrane IDA
IDA: Inferred from direct assay
11604140 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

  • PIP5K1-gamma

  • PIP5KIgamma

  • phosphatidylinositol 4-phosphate 5-kinase type I gamma

  • ptdIns(4)P-5-kinase 1 gamma

  • ptdIns(4)P-5-kinase gamma

  • ptdInsPKIgamma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-110150 UNC3230 Inhibitor 99.39% Unkown
HY-163476 PIP5K1C-IN-1 Inhibitor 98.71% Unkown
HY-163943 UNI418 Inhibitor 99.61% Unkown
HY-163477 PIP5K1C-IN-2 Inhibitor / Unkown
HY-E70633 PIP5K1C Recombinant Human Active Lipid Kinase / Unkown
HY-RS10568 PIP5K1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19283 Pip5k1c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25773 Pip5k1c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pip5k1c NCBI NCBI:23396