Tnn - tenascin N Gene

Also Known as Tnw; TN-W; tenascin-W

Species: Mus musculus

Gene Type: protein coding
Gene ID: 329278

Summary

Enables identical protein binding activity and Integrin binding activity. Involved in several processes, including generation of neurons; negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation; and negative regulation of osteoblast differentiation. Acts upstream of or within axonogenesis and cell-matrix adhesion. Located in several cellular components, including CA3 pyramidal cell dendrite; hippocampal mossy fiber expansion; and neuronal cell body. Is expressed in several structures, including forelimb pre-cartilage condensation; metanephros; palatal shelf; skeleton; and spleen. Orthologous to human TNN (tenascin N). [provided by Alliance of Genome Resources, Apr 2022]

Tnn Products (1)

mRNA Protein Name
NM_177839.3 NP_808507.2 tenascin-N precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IDA
IDA: Inferred from direct assay
14709716 MGI
enables integrin binding IDA
IDA: Inferred from direct assay
14709716 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axonogenesis IDA
IDA: Inferred from direct assay
12812753 MGI
acts upstream of or within cell-matrix adhesion IDA
IDA: Inferred from direct assay
14531729 MGI
involved in dendrite self-avoidance IDA
IDA: Inferred from direct assay
12812753 MGI
involved in negative regulation of canonical Wnt signaling pathway IDA
IDA: Inferred from direct assay
17395156 MGI
involved in negative regulation of neuron migration IDA
IDA: Inferred from direct assay
12812753 MGI
involved in negative regulation of osteoblast differentiation IDA
IDA: Inferred from direct assay
17395156 MGI
involved in negative regulation of osteoblast proliferation IDA
IDA: Inferred from direct assay
17395156 MGI
involved in neuron migration IDA
IDA: Inferred from direct assay
12812753 MGI
involved in neuron projection extension IDA
IDA: Inferred from direct assay
12812753 MGI
involved in osteoblast development IDA
IDA: Inferred from direct assay
17395156 MGI
involved in positive regulation of neuron projection development IDA
IDA: Inferred from direct assay
12812753 MGI
involved in regulation of bone development IDA
IDA: Inferred from direct assay
17395156 MGI
involved in regulation of cell adhesion IDA
IDA: Inferred from direct assay
14709716 MGI
involved in regulation of cell migration IDA
IDA: Inferred from direct assay
14709716 MGI
involved in regulation of smooth muscle tissue development IDA
IDA: Inferred from direct assay
14709716 MGI
Cellular Component GO Annotation Evidence References Source
located in CA3 pyramidal cell dendrite IDA
IDA: Inferred from direct assay
12812753 MGI
located in cell surface IDA
IDA: Inferred from direct assay
12812753 MGI
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
14709716 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
14709716 MGI
located in hippocampal mossy fiber expansion IDA
IDA: Inferred from direct assay
12812753 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
12812753 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
12812753 MGI
part of tenascin complex IPI
IPI: Inferred from physical interaction
14709716 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tenascin-N

  • TN-N

  • tenasin W

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14847 TNN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17047 Tro Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18901 Tnn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25392 Tnn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnn NCBI NCBI:63923