2. Gene
  3. AMIGO2 - adhesion molecule with Ig like domain 2 Gene

AMIGO2 - adhesion molecule with Ig like domain 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ALI1; DEGA; AMIGO-2

Gene ID: 347902 | Gene type: protein coding

About AMIGO2

Cytogenetic location: 12q13.11 Genomic coordinates (GRCh38): 12:47,075,707-47,079,959 (from NCBI)

This gene has 3 transcripts (splice variants), 168 orthologues and 2 paralogues. Broad expression in gall bladder (RPKM 9.4), urinary bladder (RPKM 8.8) and 23 other tissues.

Summary

Predicted to be involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and negative regulation of programmed cell death. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in nucleus and plasma membrane. Predicted to be integral component of membrane. Biomarker of gastric adenocarcinoma. [provided by Alliance of Genome Resources, Apr 2022]

AMIGO2 Products(3)

mRNA Protein Name
NM_001143668.1 NP_001137140.1 amphoterin-induced protein 2 precursor
NM_001370299.1 NP_001357228.1 amphoterin-induced protein 2 precursor
NM_181847.4 NP_862830.1 amphoterin-induced protein 2 precursor

AMIGO2 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (94 - 153)

LRR_1

LRR_1: Leucine Rich Repeat (166 - 183)

Ig_2

Ig_2: Immunoglobulin domain (300 - 378)

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  • 522 a.a.
Protein Preferred Names Protein Names

amphoterin-induced protein 2

alivin 1

Recombinant AMIGO2 Proteins

Cat. No. Product Name Accession Purity
HY-P7495 AMIGO2 Protein, Human (HEK293, His) Q86SJ2 (V40-A392) ≥95%
HY-P7496 AMIGO2 Protein, Human (HEK293, Fc) Q86SJ2 (G39-H393) ≥95%

Related Diseases

Diseases Alias
Gastric Adenocarcinoma

Adenocarcinoma Of Stomach

Stomach Adenocarcinoma

Adenocarcinoma Gastric

Intestinal Type Adenocarcinoma Of Unspecified Site

Diffuse Type Adenocarcinoma Of Unspecified Site
Adenocarcinoma

Adenocarcinomas

Adenoacanthoma Of Unspecified Site

Adenocarcinoid Of Unspecified Site

Adenocarcinoid Tumour Of Unspecified Site

Adenocarcinoma And Carcinoid Combined Of Unspecified Site

Adenocarcinoma Nos
Parkinson Disease 8, Autosomal Dominant

Parkinson Disease 8

Autosomal Dominant Parkinson Disease 8

PARK8

Parkinson'S Disease 8

Autosomal Dominant Parkinson'S Disease 8

Parkinson Disease-8

Parkinson Disease, Type 8, Autosomal Dominant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00658 AMIGO2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta AMIGO2 VGNC VGNC:69680
Rattus norvegicus AMIGO2 RGD RGD:727911
Mus musculus AMIGO2 MGD MGI:2145995
Bos taurus AMIGO2 VGNC VGNC:25866
Felis catus AMIGO2 VGNC VGNC:59766
Canis familiaris AMIGO2 VGNC VGNC:37832
Macaca fascicularis AMIGO2 NCBI
Others AMIGO2 NCBI