Cadm2 - cell adhesion molecule 2 Gene

Also Known as Igsf4d; Necl-3; SynCAM 2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360687

Summary

Involved in brain development. Located in axon; cytoplasm; and neuronal cell body membrane. Human ortholog(s) of this gene implicated in autism spectrum disorder; malignant astrocytoma; obesity; psoriasis; and type 2 diabetes mellitus. Orthologous to human CADM2 (cell adhesion molecule 2). [provided by Alliance of Genome Resources, Apr 2022]

Cadm2 Products (1)

mRNA Protein Name
NM_001047102.2 NP_001040567.1 cell adhesion molecule 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17724124 RGD
Biological Process GO Annotation Evidence References Source
involved in synaptic membrane adhesion IDA
IDA: Inferred from direct assay
18003830 RGD
involved in synaptic membrane adhesion IEP
IEP: Inferred from expression pattern
18003830 RGD
involved in synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
18003830 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
18003830 RGD
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
18003830 RGD
NOT located in axon IDA
IDA: Inferred from direct assay
17724124 RGD
located in axon IDA
IDA: Inferred from direct assay
17967169 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
18003830 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
18003830 RGD
located in neuronal cell body membrane IDA
IDA: Inferred from direct assay
17724124 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
18003830 RGD
is active in postsynaptic membrane IMP
IMP: Inferred from mutant phenotype
18003830 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell adhesion molecule 2

  • immunoglobulin superfamily member 4D

  • immunoglobulin superfamily, member 4

  • nectin-like protein 3

  • synaptic cell adhesion molecule 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01820 CADM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19414 Cadm2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25906 Cadm2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cadm2 NCBI NCBI:253559