2. Gene
  3. PDGFRA - platelet derived growth factor receptor alpha Gene

PDGFRA - platelet derived growth factor receptor alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 442860 | Gene type: protein coding

About PDGFRA

Primary_assembly 13: 47,340,084-47,386,176 forward strand.ROS_Cfam_1.0:CM025112.1

This gene has 2 transcripts (splice variants), 204 orthologues and 54 paralogues.

PDGFRA Products(8)

mRNA Protein Name
XM_038685630.1 XP_038541558.1 platelet-derived growth factor receptor alpha
XM_038685629.1 XP_038541557.1 platelet-derived growth factor receptor alpha
XM_038685627.1 XP_038541555.1 platelet-derived growth factor receptor alpha
XM_038685628.1 XP_038541556.1 platelet-derived growth factor receptor alpha
XM_038685628.1 XP_038541556.1 platelet-derived growth factor receptor alpha
XM_038685630.1 XP_038541558.1 platelet-derived growth factor receptor alpha
XM_038685627.1 XP_038541555.1 platelet-derived growth factor receptor alpha
XM_038685629.1 XP_038541557.1 platelet-derived growth factor receptor alpha

PDGFRA Protein Structure

Ig_3

Ig_3: pfam13927 (27 - 99)

Ig

Ig: cl11960 (211 - 309)

Ig

Ig: cd00096 (230 - 234)

Ig

Ig: cd00096 (243 - 247)

Ig

Ig: cd00096 (272 - 276)

Ig

Ig: cd00096 (286 - 291)

Ig

Ig: cd00096 (301 - 304)

Ig4_PDGFR

Ig4_PDGFR: cd05859 (312 - 412)

PTKc_PDGFR_alpha

PTKc_PDGFR_alpha: cd05105 (554 - 955)

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  • 1089 a.a.
Protein Preferred Names Protein Names

platelet-derived growth factor receptor alpha

Related Agents

Approval
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13001 Quizartinib 99.08% Yes
HY-101561 Avapritinib Inhibitor 99.85% Yes
HY-112306 Ripretinib 98.90% Yes
HY-14217 Quizartinib dihydrochloride 99.81% Unkown
HY-13001R Quizartinib (Standard) / Unkown
Pre-clinical Phase
Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-132166 Velzatinib Inhibitor 99.40% Unkown
HY-RS10254 PDGFRA Human Pre-designed siRNA Set A / Unkown
HY-108444 (Z)-FeCP-oxindole Inhibitor 99.62% Unkown
HY-13001S Quizartinib-d8 / Unkown
HY-108444A (E)-FeCP-oxindole Inhibitor / Unkown
HY-149510 MET/PDGFRA-IN-1 / Unkown
HY-149511 MET/PDGFRA-IN-2 / Unkown
HY-170911 KIT/PDGFRA-IN-1 Inhibitor / Unkown
HY-173124 CDK2/FLT4/PDGFRA-IN-1 / Unkown
HY-175212 PDGFRA-IN-1 Inhibitor / Unkown
HY-181108 GSK190937 Inhibitor / Unkown
HY-181587 PDGFRA/CAIX/XII-IN-1 / Unkown
HY-181886 AK177 / Unkown
HY-RS10255 Pdgfra Mouse Pre-designed siRNA Set A / Unkown
HY-RS10256 PDGFRA Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174549 Human PDGFRA mRNA / Unkown
HY-W754911 Avapritinib-d3 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDGFRA NCBI NCBI:5156
Macaca fascicularis PDGFRA NCBI NCBI:102138392
Mus musculus PDGFRA NCBI NCBI:18595
Rattus norvegicus PDGFRA NCBI NCBI:25267