PDGFRA - platelet derived growth factor receptor alpha Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 442860
About PDGFRA
Primary_assembly 13: 47,340,084-47,386,176 forward strand.ROS_Cfam_1.0:CM025112.1
This gene has 2 transcripts (splice variants), 204 orthologues and 54 paralogues.
PDGFRA Products (8)
| mRNA | Protein | Name |
|---|---|---|
| XM_038685630.1 | XP_038541558.1 | platelet-derived growth factor receptor alpha |
| XM_038685629.1 | XP_038541557.1 | platelet-derived growth factor receptor alpha |
| XM_038685627.1 | XP_038541555.1 | platelet-derived growth factor receptor alpha |
| XM_038685628.1 | XP_038541556.1 | platelet-derived growth factor receptor alpha |
| XM_038685628.1 | XP_038541556.1 | platelet-derived growth factor receptor alpha |
| XM_038685630.1 | XP_038541558.1 | platelet-derived growth factor receptor alpha |
| XM_038685627.1 | XP_038541555.1 | platelet-derived growth factor receptor alpha |
| XM_038685629.1 | XP_038541557.1 | platelet-derived growth factor receptor alpha |
PDGFRA Protein Structure
Ig_3
Ig_3: pfam13927 (27 - 99)
Ig
Ig: cl11960 (211 - 309)
Ig
Ig: cd00096 (230 - 234)
Ig
Ig: cd00096 (243 - 247)
Ig
Ig: cd00096 (272 - 276)
Ig
Ig: cd00096 (286 - 291)
Ig
Ig: cd00096 (301 - 304)
Ig4_PDGFR
Ig4_PDGFR: cd05859 (312 - 412)
PTKc_PDGFR_alpha
PTKc_PDGFR_alpha: cd05105 (554 - 955)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1089 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
platelet-derived growth factor receptor alpha |
|
Related Agents
- Approval
- Pre-clinical Phase
Approval
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-13001 | Quizartinib | 99.08% | Yes | |
| HY-101561 | Avapritinib | Inhibitor | 99.85% | Yes |
| HY-112306 | Ripretinib | 98.90% | Yes | |
| HY-14217 | Quizartinib dihydrochloride | 99.81% | Unkown | |
| HY-13001R | Quizartinib (Standard) | / | Unkown |
Pre-clinical Phase
Bioactive Molecules
(17)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-132166 | Velzatinib | Inhibitor | 99.40% | Unkown |
| HY-RS10254 | PDGFRA Human Pre-designed siRNA Set A | / | Unkown | |
| HY-108444 | (Z)-FeCP-oxindole | Inhibitor | 99.62% | Unkown |
| HY-13001S | Quizartinib-d8 | / | Unkown | |
| HY-108444A | (E)-FeCP-oxindole | Inhibitor | / | Unkown |
| HY-149510 | MET/PDGFRA-IN-1 | / | Unkown | |
| HY-149511 | MET/PDGFRA-IN-2 | / | Unkown | |
| HY-170911 | KIT/PDGFRA-IN-1 | Inhibitor | / | Unkown |
| HY-173124 | CDK2/FLT4/PDGFRA-IN-1 | / | Unkown | |
| HY-175212 | PDGFRA-IN-1 | Inhibitor | / | Unkown |
| HY-181108 | GSK190937 | Inhibitor | / | Unkown |
| HY-181587 | PDGFRA/CAIX/XII-IN-1 | 98.10% | Unkown | |
| HY-181886 | AK177 | / | Unkown | |
| HY-RS10255 | Pdgfra Mouse Pre-designed siRNA Set A | / | Unkown | |
| HY-RS10256 | PDGFRA Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-174549 | Human PDGFRA mRNA | / | Unkown | |
| HY-W754911 | Avapritinib-d3 | Inhibitor | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service