MYL5 - myosin light chain 5 Gene

Also Known as MYLC2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4636

About MYL5

Cytogenetic location: 4p16.3 Genomic coordinates (GRCh38): 4:674,542-682,028 (from NCBI)

This gene has 9 transcripts (splice variants), 107 orthologues and 7 paralogues. Ubiquitous expression in fat (RPKM 6.7), duodenum (RPKM 6.7) and 25 other tissues.

Summary

This gene encodes one of the Myosin light chains, a component of the hexameric ATPase cellular motor protein Myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia. [provided by RefSeq, Jul 2008]

MYL5 Products (11)

mRNA Protein Name
NM_001363650.2 NP_001350579.1 myosin light chain 5 isoform 2
NM_001395441.1 NP_001382370.1 myosin light chain 5 isoform 1
NM_001395442.1 NP_001382371.1 myosin light chain 5 isoform 1
NM_001395443.1 NP_001382372.1 myosin light chain 5 isoform 1
NM_001395444.1 NP_001382373.1 myosin light chain 5 isoform 2
NM_001395445.1 NP_001382374.1 myosin light chain 5 isoform 2
NM_001395446.1 NP_001382375.1 myosin light chain 5 isoform 2
NM_001395447.1 NP_001382376.1 myosin light chain 5 isoform 2
NM_001395448.1 NP_001382377.1 myosin light chain 5 isoform 2
NM_001395449.1 NP_001382378.1 myosin light chain 5 isoform 2
NM_002477.2 NP_002468.1 myosin light chain 5 isoform 1

MYL5 Protein Structure

EF-hand_6

EF-hand_6: EF-hand domain (34 - 62)

EF-hand_6

EF-hand_6: EF-hand domain (106 - 130)

  • 0
  • 100
  • 173 a.a.
Protein Preferred Names Protein Names

myosin light chain 5

  • myosin regulatory light chain 5

MYL5 Antibodies

Cat. No. Product Name Application Reactivity
HY-P85656 Myosin Heavy Chain Antibody (YA5348) ICC/IF Human, Mouse, Rat, FruitFly, Nematode

Related Diseases

Diseases Alias
Myopathy, Centronuclear, 2

  • Myopathy, Centronuclear, Autosomal Recessive

  • Autosomal Recessive Centronuclear Myopathy

  • CNM2

  • Centronuclear Myopathy 2

  • Ar-Cnm

  • Myotubular Myopathy, Autosomal Recessive

  • Autosomal Recessive Myotubular Myopathy

  • Centronuclear Myopathy Autosomal Recessive

  • Myopathy, Centronuclear, Type 2
Cardiomyopathy, Familial Hypertrophic, 1

  • Asymmetric Septal Hypertrophy

  • Familial Hypertrophic Cardiomyopathy

  • Hypertrophic Cardiomyopathy 1

  • CMH1

  • Hypertrophic Cardiomyopathy 19

  • CMH

  • Ventricular Hypertrophy, Hereditary

  • Ash

  • Hypertrophic Subaortic Stenosis, Idiopathic

  • Cardiomyopathy, Familial Hypertrophic

  • Cardiomyopathy, Hypertrophic, 1, Digenic

  • Cardiomyopathy, Familial Hypertrophic 1

  • Hcm

  • Hereditary Ventricular Hypertrophy

  • Idiopathic Hypertrophic Subaortic Stenosis

  • Hypertrophic Cardiomyopathy

  • Cardiomyopathy, Hypertrophic, Familial

  • Cardiomyopathy, Hypertrophic, 1

  • Familial Asymmetric Septal Hypertrophy

  • Heritable Hypertrophic Cardiomyopathy

  • Fhc

  • Cardiomyopathy, Hypertrophic, Familial, Type 1
Hypertrophic Cardiomyopathy

  • Hypertrophic Obstructive Cardiomyopathy

  • Cardiomyopathy, Hypertrophic

  • Cardiomyopathy Hypertrophic Obstructive

  • Cardiomyopathy, Hypertrophic, Familial

  • Idiopathic Myocardial Hypertrophy

  • Idiopathic Hypertrophic Cardiomyopathy

  • Obstructive Idiopathic Hypertrophic Cardiomyopathy

  • Obstructive Cardiomyopathy

  • Idiopathic Hypertrophic Subaortic Stenosis

  • Muscular Subaortic Stenosis

  • Hypertrophic Obstructive Subaortic Stenosis
Dilated Cardiomyopathy

  • Familial Dilated Cardiomyopathy

  • Primary Dilated Cardiomyopathy

  • Idiopathic Dilated Cardiomyopathy

  • Congestive Cardiomyopathy

  • Idiopathic Dilation Cardiomyopathy

  • Primary Familial Dilated Cardiomyopathy

  • Cardiomyopathy, Dilated

  • DCM

  • Cardiomyopathy, Familial Dilated

  • Dilated Cardiomyopathy, Familial

  • Hypokinetic Dilated Cardiomyopathy, Familial

  • Familial Idiopathic Cardiomyopathy

  • Fdc

  • Cardiomyopathy, Familial Idiopathic

  • Idiopathic Cardiomegaly

  • Dilated Congestive Cardiomyopathy

  • Chronic Dilated Cardiomyopathy

  • Ccm - [Congestive Cardiomyopathy]

  • Cocm - [Congestive Cardiomyopathy]

  • Dcm - [Dilated Cardiomyopathy]

  • Dilated-Hypokinetic Cardiomyopathy

  • Congestive Idiopathic Cardiomyopathy

  • Primary Idiopathic Dilated Cardiomyopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08917 MYL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown