ERBB3 - erb-b2 receptor tyrosine kinase 3 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 481105

About ERBB3

Primary_assembly 10: 417,394-431,614 forward strand.ROS_Cfam_1.0:CM025109.1

This gene has 2 transcripts (splice variants), 280 orthologues and 54 paralogues.

ERBB3 Products (1)

mRNA Protein Name
XM_038678968.1 XP_038534896.1 LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3 isoform X1

ERBB3 Protein Structure

Recep_L_domain

Recep_L_domain: pfam01030 (55 - 166)

Furin-like

Furin-like: pfam00757 (174 - 328)

Recep_L_domain

Recep_L_domain: pfam01030 (352 - 473)

GF_recep_IV

GF_recep_IV: pfam14843 (498 - 629)

TM_ErbB3

TM_ErbB3: cd12095 (637 - 675)

PTK_HER3

PTK_HER3: cd05111 (700 - 978)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1339 a.a.
Protein Preferred Names Protein Names

receptor tyrosine-protein kinase erbB-3

LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3

  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0426A Olopatadine hydrochloride 99.83% Unkown
HY-W062109 Olopatadine 98.94% Unkown
HY-B0426AR Olopatadine hydrochloride (Standard) / Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-118998 TX2-121-1 Inhibitor / Phase 3
HY-13050 Sapitinib Inhibitor 99.93% Phase 2
Bioactive MoleculesInhibitory Antibodies (6)
Cat. No. Product Name Effect
Purity Phase
HY-P99275 Patritumab Inhibitor 99.28% Phase 3
HY-P99672 Istiratumab Inhibitor 98.45% Phase 2
HY-P991240 CDX-3379 Inhibitor 99.38% Phase 2
HY-P991524 MM-111 Inhibitor / Phase 2
HY-P99304 Lumretuzumab Inhibitor ≥99.0% Phase 1
HY-P991244 REGN-1400 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100848 TX1-85-1 Inhibitor 99.65% Unkown
HY-18609 PD158780 Inhibitor 99.47% Unkown
HY-E70715 ERBB2 775YVMA776 Recombinant Human Active Protein Kinase / Unkown
HY-13050A Sapitinib fumarate Inhibitor / Unkown
HY-B0426AS2 Olopatadine-d6 hydrochloride / Unkown
HY-RS04469 ERBB3 Human Pre-designed siRNA Set A / Unkown
HY-RS04470 Erbb3 Mouse Pre-designed siRNA Set A / Unkown
HY-RS04471 Erbb3 Rat Pre-designed siRNA Set A / Unkown
HY-W062109S Olopatadine-d6 / Unkown
HY-B0426AS Olopatadine-d3 hydrochloride / Unkown
Bioactive MoleculesInhibitory Antibodies (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991159 Ruzaltatug Inhibitor 95.69% Unkown
HY-P992128 Rinumafusp alfa Inhibitor / Unkown
HY-P991241 Anti-ERBB3/HER3 (29Z6) Inhibitor / Unkown
HY-P991243 MP-RM-1 Inhibitor 96.29% Unkown
HY-P991245 Anti-ERBB3/HER3 (SGP1) Inhibitor / Unkown
HY-P991983 DB-1310 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ERBB3 NCBI NCBI:2065