ERBB3 - erb-b2 receptor tyrosine kinase 3 Gene

Canis lupus familiaris (sub-species: familiaris)

Gene ID: 481105 | Gene type: protein coding

About ERBB3

Primary_assembly 10: 417,394-431,614 forward strand.ROS_Cfam_1.0:CM025109.1

This gene has 2 transcripts (splice variants), 280 orthologues and 54 paralogues.

mRNA	Protein	Name
XM_038678968.1	XP_038534896.1	LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3 isoform X1

Recep_L_domain

Furin-like

Recep_L_domain

GF_recep_IV

TM_ErbB3

PTK_HER3

Protein Preferred Names

Protein Names

receptor tyrosine-protein kinase erbB-3

LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-B0426A	Olopatadine hydrochloride	99.83%	Unkown
HY-W062109	Olopatadine	98.94%	Unkown
HY-B0426AR	Olopatadine hydrochloride (Standard)	/	Unkown

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-118998	TX2-121-1	Inhibitor	/	Phase 3
HY-13050	Sapitinib	Inhibitor	99.93%	Phase 2

Inhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99275	Patritumab	Inhibitor	99.28%	Phase 3
HY-P99268	Seribantumab		96.043%	Phase 2
HY-P99672	Istiratumab	Inhibitor	98.45%	Phase 2
HY-P991240	CDX-3379	Inhibitor	99.38%	Phase 2
HY-P99304	Lumretuzumab	Inhibitor	≥99.0%	Phase 1
HY-P991244	REGN-1400	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-100848	TX1-85-1	Inhibitor	99.65%	Unkown
HY-18609	PD158780	Inhibitor	99.47%	Unkown
HY-E70715	ERBB2 775YVMA776 Recombinant Human Active Protein Kinase		/	Unkown
HY-13050A	Sapitinib fumarate	Inhibitor	/	Unkown
HY-B0426AS2	Olopatadine-d6 hydrochloride		/	Unkown
HY-RS04469	ERBB3 Human Pre-designed siRNA Set A		/	Unkown
HY-RS04470	Erbb3 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS04471	Erbb3 Rat Pre-designed siRNA Set A		/	Unkown
HY-W062109S	Olopatadine-d6		/	Unkown
HY-B0426AS	Olopatadine-d3 hydrochloride		/	Unkown

Inhibitory Antibodies (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P991159	Ruzaltatug	Inhibitor	/	Unkown
HY-P991241	Anti-ERBB3/HER3 (29Z6)	Inhibitor	/	Unkown
HY-P991243	MP-RM-1	Inhibitor	96.29%	Unkown
HY-P991245	Anti-ERBB3/HER3 (SGP1)	Inhibitor	/	Unkown
HY-P991524	MM-111	Inhibitor	/	Unkown
HY-P991983	DB-1310 Antibody		/	Unkown
HY-P992128	Rinumafusp alfa	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	ERBB3	NCBI	NCBI:2065
Mus musculus	ERBB3	NCBI	NCBI:13867
Rattus norvegicus	ERBB3	NCBI	NCBI:29496
Macaca mulatta	ERBB3	NCBI	NCBI:711407

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