2. Gene
  3. MAP4K4 - mitogen-activated protein kinase kinase kinase kinase 4 Gene

MAP4K4 - mitogen-activated protein kinase kinase kinase kinase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 481331 | Gene type: protein coding

About MAP4K4

Primary_assembly 10: 41,955,875-42,144,609 reverse strand.ROS_Cfam_1.0:CM025109.1

This gene has 3 transcripts (splice variants), 281 orthologues and 36 paralogues.

MAP4K4 Products(100)

mRNA Protein Name
XM_038680216.1 XP_038536144.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X4
XM_038680240.1 XP_038536168.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X26
XM_038680220.1 XP_038536148.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X8
XM_038680262.1 XP_038536190.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X46
XM_038680250.1 XP_038536178.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X35
XM_038680228.1 XP_038536156.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X16
XM_038680266.1 XP_038536194.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X50
XM_038680224.1 XP_038536152.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X12
XM_038680223.1 XP_038536151.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X11
XM_038680233.1 XP_038536161.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X20
XM_038680222.1 XP_038536150.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X10
XM_038680214.1 XP_038536142.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X2
XM_038680237.1 XP_038536165.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X24
XM_038680236.1 XP_038536164.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X23
XM_038680263.1 XP_038536191.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X47
XM_038680218.1 XP_038536146.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X6
XM_038680245.1 XP_038536173.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X31
XM_038680254.1 XP_038536182.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X39
XM_038680265.1 XP_038536193.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X49
XM_038680227.1 XP_038536155.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X15
XM_038680246.1 XP_038536174.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X32
XM_038680231.1 XP_038536159.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X19
XM_038680247.1 XP_038536175.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X33
XM_038680213.1 XP_038536141.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X1
XM_038680242.1 XP_038536170.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X28
XM_038680215.1 XP_038536143.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X3
XM_038680226.1 XP_038536154.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X14
XM_038680261.1 XP_038536189.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X45
XM_038680225.1 XP_038536153.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X13
XM_038680248.1 XP_038536176.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X34
XM_038680217.1 XP_038536145.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X5
XM_038680257.1 XP_038536185.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X42
XM_038680258.1 XP_038536186.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X43
XM_038680235.1 XP_038536163.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X22
XM_038680256.1 XP_038536184.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X41
XM_038680241.1 XP_038536169.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X27
XM_038680244.1 XP_038536172.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X30
XM_038680259.1 XP_038536187.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X44
XM_038680239.1 XP_038536167.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X25
XM_038680234.1 XP_038536162.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X21
XM_038680221.1 XP_038536149.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X9
XM_038680230.1 XP_038536158.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X18
XM_038680253.1 XP_038536181.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X38
XM_038680255.1 XP_038536183.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X40
XM_038680219.1 XP_038536147.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X7
XM_038680252.1 XP_038536180.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X37
XM_038680251.1 XP_038536179.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X36
XM_038680243.1 XP_038536171.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X29
XM_038680229.1 XP_038536157.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X17
XM_038680264.1 XP_038536192.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X48
XM_038680215.1 XP_038536143.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X3
XM_038680214.1 XP_038536142.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X2
XM_038680216.1 XP_038536144.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X4
XM_038680225.1 XP_038536153.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X13
XM_038680213.1 XP_038536141.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X1
XM_038680251.1 XP_038536179.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X36
XM_038680231.1 XP_038536159.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X19
XM_038680220.1 XP_038536148.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X8
XM_038680246.1 XP_038536174.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X32
XM_038680241.1 XP_038536169.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X27
XM_038680223.1 XP_038536151.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X11
XM_038680229.1 XP_038536157.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X17
XM_038680230.1 XP_038536158.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X18
XM_038680228.1 XP_038536156.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X16
XM_038680218.1 XP_038536146.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X6
XM_038680264.1 XP_038536192.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X48
XM_038680255.1 XP_038536183.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X40
XM_038680237.1 XP_038536165.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X24
XM_038680254.1 XP_038536182.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X39
XM_038680236.1 XP_038536164.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X23
XM_038680221.1 XP_038536149.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X9
XM_038680240.1 XP_038536168.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X26
XM_038680222.1 XP_038536150.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X10
XM_038680239.1 XP_038536167.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X25
XM_038680247.1 XP_038536175.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X33
XM_038680245.1 XP_038536173.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X31
XM_038680244.1 XP_038536172.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X30
XM_038680243.1 XP_038536171.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X29
XM_038680224.1 XP_038536152.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X12
XM_038680252.1 XP_038536180.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X37
XM_038680234.1 XP_038536162.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X21
XM_038680227.1 XP_038536155.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X15
XM_038680219.1 XP_038536147.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X7
XM_038680226.1 XP_038536154.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X14
XM_038680217.1 XP_038536145.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X5
XM_038680257.1 XP_038536185.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X42
XM_038680253.1 XP_038536181.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X38
XM_038680235.1 XP_038536163.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X22
XM_038680259.1 XP_038536187.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X44
XM_038680242.1 XP_038536170.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X28
XM_038680258.1 XP_038536186.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X43
XM_038680248.1 XP_038536176.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X34
XM_038680262.1 XP_038536190.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X46
XM_038680263.1 XP_038536191.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X47
XM_038680261.1 XP_038536189.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X45
XM_038680250.1 XP_038536178.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X35
XM_038680233.1 XP_038536161.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X20
XM_038680266.1 XP_038536194.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X50
XM_038680265.1 XP_038536193.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X49
XM_038680256.1 XP_038536184.1 mitogen-activated protein kinase kinase kinase kinase 4 isoform X41

MAP4K4 Protein Structure

PKc_like

PKc_like: cl21453 (7 - 288)

CNH

CNH: smart00036 (1063 - 1369)

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  • 1390 a.a.
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase kinase 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-160623 Rentosertib 99.96% Unkown
HY-100343 GNE-495 Inhibitor 99.49% Unkown
HY-19562 PF-06260933 Inhibitor 99.39% Unkown
HY-111754 DMX-5804 Inhibitor 99.83% Unkown
HY-125012 MAP4K4-IN-3 Inhibitor 99.77% Unkown
HY-168972 Famlasertib Inhibitor 99.94% Unkown
HY-132290 TGFβRI-IN-3 Inhibitor 98.21% Unkown
HY-156715 MASTL-IN-1 Inhibitor 99.54% Unkown
HY-U00428A GNE 220 hydrochloride Inhibitor 98.22% Unkown
HY-W003471 Pyrrolo[2,1-f][1,2,4]triazin-4-amine Inhibitor / Unkown
HY-137340 WH-10417-099 Degrader 98.14% Unkown
HY-156523 TNIK&MAP4K4-IN-1 99.73% Unkown
HY-U00428 GNE 220 Inhibitor / Unkown
HY-123965 PF-06745013 Inhibitor / Unkown
HY-162922 MAP4K4-IN-6 Inhibitor / Unkown
HY-RS08080 MAP4K4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08081 Map4k4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08082 Map4k4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W402208 MAP4K4-IN-7 Inhibitor / Unkown
HY-178775 PI4K-IN-3 Inhibitor / Unkown
HY-19562A PF-06260933 hydrochloride Inhibitor 99.42% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MAP4K4 NCBI NCBI:9448