PF-06745013
PF-06745013 (Compound 37) is a MAP4K4 inhibitor without time-dependent inhibition (TDI) risk of CYP3A4 (IC50 of 0.4 nM for MAP4K4). PF-06745013 has no accumulation CNS-impaired and non-ATP competitive activities in mouse models. PF-06745013 can be used for inflammatory diseases like diabetes and cancers research.
For research use only. We do not sell to patients.
- CAS No.: 2089334-01-8
- Formula: C21H19ClN2O3
- Molecular Weight:382.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All MAP4K Isoforms
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Biological Activity
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MAP4K4 0.4 nM (IC50) |
Chemical Information
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CAS No. 2089334-01-8
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Molecular Weight 382.84
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Formula C21H19ClN2O3
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SMILES
O=C(C(C)(C)OC1=CC=C(C2=CN=C(C(C3=CC=C(Cl)C=C3)=C2)N)C=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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