CDK12 - cyclin dependent kinase 12 Gene

Also Known as CRKRS

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 491027

About CDK12

Primary_assembly 9: 23,711,344-23,772,894 reverse strand.ROS_Cfam_1.0:CM025108.1

This gene has 2 transcripts (splice variants), 206 orthologues and 25 paralogues.

CDK12 Products (2)

mRNA Protein Name
XM_038676614.1 XP_038532542.1 cyclin-dependent kinase 12 isoform X2
XM_038676613.1 XP_038532541.1 cyclin-dependent kinase 12 isoform X1

CDK12 Protein Structure

STKc_CDK12

STKc_CDK12: cd07864 (718 - 1019)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1490 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 12

  • Cdc2-related kinase, arginine/serine-rich

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-138293 SY-5609 Inhibitor 99.93% Phase 1

Pre-clinical Phase

Bioactive Molecules (46)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-80013 THZ1 Inhibitor 99.84% Unkown
HY-103618 THZ531 Inhibitor 99.86% Unkown
HY-130250 SR-4835 Inhibitor 99.73% Unkown
HY-139039 BSJ-4-116 Inhibitor 99.87% Unkown
HY-80013A THZ1 Hydrochloride Inhibitor 99.06% Unkown
HY-168555 YJ1206 Degrader 97.26% Unkown
HY-112626 CDK12-IN-2 Inhibitor 99.36% Unkown
HY-153244 MFH290 Inhibitor 98.29% Unkown
HY-151110A PROTAC CDK12/13 Degrader-1 TFA Degrader 99.12% Unkown
HY-112261 CDK12-IN-3 Inhibitor 99.86% Unkown
HY-163944 LL-K12-18 Inhibitor 98.42% Unkown
HY-162706 BSJ-5-63 Degrader 99.97% Unkown
HY-145072 BSJ-01-175 Inhibitor 99.88% Unkown
HY-168162 ZLC491 Degrader 98.51% Unkown
HY-139329 CDK12-IN-6 Inhibitor 99.15% Unkown
HY-139980 CDK9-IN-13 Inhibitor 99.94% Unkown
HY-171787A PPA-037 TFA Inhibitor 99.42% Unkown
HY-151110 PROTAC CDK12/13 Degrader-1 Degrader 98.01% Unkown
HY-117203A CDK12-IN-E9 Inhibitor 99.71% Unkown
HY-155787 SHR5428 Inhibitor 99.80% Unkown
HY-139328 CDK12-IN-5 Inhibitor 98.03% Unkown
HY-144691 PP-C8 Inhibitor 99.99% Unkown
HY-172970 HQY1428 Inhibitor 99.65% Unkown
HY-168556 YJ9069 Degrader / Unkown
HY-173059 CDK12/13-IN-3 Inhibitor 99.14% Unkown
HY-142696 CDK6/PIM1-IN-1 Inhibitor / Unkown
HY-171787 PPA-037 Inhibitor / Unkown
HY-171786 CDK12-IN-8 Inhibitor 99.52% Unkown
HY-181035 DN1679 Degrader / Unkown
HY-150948 CDK12 ligand-2 Ligand / Unkown
HY-168658 CDK12/13 ligand 2 Degrader / Unkown
HY-139327 CDK12-IN-4 Inhibitor / Unkown
HY-181036 CDK12/13 ligand 3 Ligand / Unkown
HY-162528 CDK12-IN-7 Inhibitor / Unkown
HY-180912 HS-36 Inhibitor / Unkown
HY-114567 GW780056X Inhibitor / Unkown
HY-173147 CDK2-IN-42 Inhibitor / Unkown
HY-150641 CDK-IN-9 Inhibitor / Unkown
HY-151878 CDK7-IN-20 Inhibitor / Unkown
HY-181405 SR-5037 Inhibitor 99.58% Unkown
HY-173042 CDK12/13-IN-2 Inhibitor / Unkown
HY-168163 CDK12/13 ligand 1 Degrader / Unkown
HY-181645 CDK12-IN-9 Inhibitor / Unkown
HY-173273 YJZ5118 Inhibitor / Unkown
HY-172224 PARP1/CDK12-IN-1 Inhibitor / Unkown
HY-176790 CDK12-Cyclin K ligand-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CDK12 NCBI NCBI:51755