PARP1/CDK12-IN-1
PARP1/CDK12-IN-1 (107) is a dual inhibitor of CDK12 and PARP1, with IC50 values of 285 nM and 34 nM for CDK12 and PARP1, respectively.
For research use only. We do not sell to patients.
- Formula: C25H23IN8O3
- Molecular Weight:610.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK12 285 nM (IC50) |
PARP1 34 nM (IC50) |
PARP1/CDK12-IN-1 (107) synergistically inhibiting TNBC cell proliferation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 610.41
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Formula C25H23IN8O3
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SMILES
NC(C1=CC=CC2=C1N=C(NC(C3=CC=CC(C(N4CCC(NC5=NC=C(N=C5)I)CC4)=O)=C3)=O)N2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PARP1/CDK12-IN-1 Related Classifications
HY-172224 Related Classifications
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