CDK12-IN-7
CDK12-IN-7 (Compound 2) is a CDK12 and CDK2 inhibitor with IC50 values of 42 and 196 nM, respectively. CDK12-IN-7 has anti-cell proliferation activity and can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3033863-94-1
- Formula: C32H32F3N9O4
- Molecular Weight:663.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK2 196 nM (IC50) |
CDK12 42 nM (IC50) |
CDK12-IN-7 inhibits A2780 cell proliferation with an IC50 value of 429 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3033863-94-1
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Molecular Weight 663.65
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Formula C32H32F3N9O4
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SMILES
O=C(NCC1=CC=CC=C1)N(C2=CC=C(N(C=CC(N3C)=O)C3=N4)C4=N2)[C@H](CC5)CC[C@@H]5NC6=NC(OC7COC7)=C(C(F)(F)F)C=N6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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