Rspo2 - R-spondin 2 Gene

Predicted to enable heparin binding activity and signaling receptor binding activity. Predicted to be involved in limb development and positive regulation of Wnt signaling pathway. Predicted to act upstream of or within several processes, including embryonic limb morphogenesis; negative regulation of odontogenesis of dentin-containing tooth; and respiratory system development. Predicted to be located in cell surface and extracellular region. Human ortholog(s) of this gene implicated in tetraamelia syndrome 2. Orthologous to human RSPO2 (R-spondin 2). [provided by Alliance of Genome Resources, Apr 2022]