2. Gene
  3. CALML5 - calmodulin like 5 Gene

CALML5 - calmodulin like 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CLSP

Gene ID: 51806 | Gene type: protein coding

About CALML5

Cytogenetic location: 10p15.1 Genomic coordinates (GRCh38): 10:5,498,697-5,499,570 (from NCBI)

This gene has 1 transcript (splice variant), 239 orthologues and 20 paralogues.

Summary

This gene encodes a novel calcium binding protein expressed in the epidermis and related to the Calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key Enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008]

CALML5 Products(1)

mRNA Protein Name
NM_017422.5 NP_059118.2 calmodulin-like protein 5

CALML5 Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (12 - 72)

EF-hand_7

EF-hand_7: EF-hand domain pair (84 - 142)

  • 0
  • 100
  • 146 a.a.
Protein Preferred Names Protein Names

calmodulin-like protein 5

calmodulin-like skin protein

Recombinant CALML5 Proteins

Cat. No. Product Name Accession Purity
HY-P76760 CALML5 Protein, Human (His) Q9NZT1 (M1-E146) ≥95%

Related Diseases

Diseases Alias
Schizophrenia 1

SCZD1

Schizophrenia Susceptibility Locus, Chromosome 5-Related

Schizophrenia 1 With Or Without An Affective Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01845 CALML5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CALML5 VGNC VGNC:56179
Mus musculus CALML5 MGD MGI:1931464
Rattus norvegicus CALML5 RGD RGD:1310047
Macaca mulatta CALML5 VGNC VGNC:70576
Canis familiaris CALML5 VGNC VGNC:38672
Others CALML5 NCBI