Lgals1 - galectin 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 56646

Summary

Enables identical protein binding activity; lactose binding activity; and laminin binding activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of erythrocyte aggregation; and response to isolation stress. Located in cell surface; cytosol; and nucleus. Biomarker of B-cell lymphoma; extrahepatic cholestasis; and lipoid nephrosis. Orthologous to human LGALS1 (Galectin 1). [provided by Alliance of Genome Resources, Apr 2022]

Lgals1 Products (1)

mRNA Protein Name
NM_019904.1 NP_063969.1 galectin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
10814697 RGD
enables lactose binding IDA
IDA: Inferred from direct assay
1955484 RGD
enables laminin binding IDA
IDA: Inferred from direct assay
1955484 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10814697 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to glucose stimulus IEP
IEP: Inferred from expression pattern
19125585 RGD
involved in cellular response to organic cyclic compound IEP
IEP: Inferred from expression pattern
17316808 RGD
involved in negative regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
1955484 RGD
involved in negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
17486104 RGD
involved in positive regulation of erythrocyte aggregation IDA
IDA: Inferred from direct assay
3800956 RGD
involved in response to axon injury IEP
IEP: Inferred from expression pattern
18850073 RGD
involved in response to isolation stress IEP
IEP: Inferred from expression pattern
19616040 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17490626 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
1955484 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

galectin-1

  • 14 kDa lectin

  • RL 14.5

  • S-Lac lectin 1

  • beta-galactoside-binding lectin L-14-I

  • gal-1

  • galaptin

  • lactose-binding lectin 1

  • lectin, galactose binding, soluble 1

  • lectin, galactoside-binding, soluble, 1

Recombinant Lgals1 Proteins

Cat. No. Product Name Accession Purity
HY-P74130 Galectin-1/LGALS1 Protein, Rat P11762 (A2-E135) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07602 LGALS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-176259 F3-PEG8-RiboTAC / Unkown
HY-RS17042 Lgals1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23487 Lgals1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lgals1 NCBI NCBI:3956