Fgf20 - fibroblast growth factor 20 Gene

Also Known as Fgf4a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 66017

Summary

Enables Fibroblast Growth Factor receptor binding activity and growth factor activity. Acts upstream of or within Fibroblast Growth Factor receptor signaling pathway; positive regulation of ERK1 and ERK2 cascade; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in renal agenesis. Orthologous to human FGF20 (Fibroblast Growth Factor 20). [provided by Alliance of Genome Resources, Apr 2022]

Fgf20 Products (1)

mRNA Protein Name
NM_023961.2 NP_076451.1 fibroblast growth factor 20

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables fibroblast growth factor receptor binding IGI
IGI: Inferred from genetic interaction
12704805 RGD
enables growth factor activity IDA
IDA: Inferred from direct assay
11032730 RGD
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within fibroblast growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
12704805 RGD
acts upstream of or within positive regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
12704805 RGD
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
12704805 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 20

  • fibroblast growth factor 4a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-169348 β-catenin-IN-8 Inhibitor / Unkown
HY-RS04897 FGF20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174701 Human FGF20 mRNA / Unkown
HY-RS19003 Fgf20 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25492 Fgf20 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf20 NCBI NCBI:26281